8T3V
Cryo-EM structure of the DHA bound FFA1-Gq complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 229 | 26569.2 | 1 | Homo sapiens | ||
| 2 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 342 | 37516.9 | 1 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | G | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 57 | 6261.2 | 1 | UniProt (P59768) Pfam (PF00631) In PDB | Homo sapiens (human) | G gamma-I |
| 4 | N | scFv16 | polymer | 266 | 28634.8 | 1 | Mus musculus | ||
| 5 | R | Free fatty acid receptor 1 | polymer | 279 | 29395.5 | 1 | UniProt (O14842) Pfam (PF00001) In PDB | Homo sapiens (human) | G-protein coupled receptor 40 |
| 6 | R | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) | |||
| 7 | R | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID | non-polymer | 328.5 | 1 | Chemie (HXA) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Gly 341 | - | expression tag |
| Ser 342 | - | expression tag |
| Ser 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 128377.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 715.1 | |
| All* | Total formula weight | 129092.8 |
