8SG1

Cryo-EM structure of CMKLR1 signaling complex

Summary for 8SG1

• Entry DOI: 10.2210/pdb8sg1/pdb
• EMDB information: 40450
• Descriptor: Chemerin-like receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total)
• Functional Keywords: gpcr, peptide agonist, chemerin9, membrane protein, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 146756.22

Authors

Zhang, X.,Zhang, C. (deposition date: 2023-04-11, release date: 2023-11-01, Last modification date: 2023-12-20)

• Primary citation: Zhang, X.,Weiss, T.,Cheng, M.H.,Chen, S.,Ambrosius, C.K.,Czerniak, A.S.,Li, K.,Feng, M.,Bahar, I.,Beck-Sickinger, A.G.,Zhang, C.; Structural basis of G protein-Coupled receptor CMKLR1 activation and signaling induced by a chemerin-derived agonist.; Plos Biol., 21:e3002188-e3002188, 2023; PubMed: 38055679; DOI: 10.1371/journal.pbio.3002188

Experimental method

ELECTRON MICROSCOPY (2.94 Å)