1T92
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![BU of 1t92 by Molmil](/molmil-images/mine/1t92) | Crystal structure of N-terminal truncated pseudopilin PulG | Descriptor: | General secretion pathway protein G, ZINC ION | Authors: | Koehler, R, Schaefer, K, Mueller, S, Vignon, G, Diederichs, K, Philippsen, A, Ringler, P, Pugsley, A.P, Engel, A, Welte, W. | Deposit date: | 2004-05-14 | Release date: | 2004-10-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure and assembly of the pseudopilin PulG. Mol.Microbiol., 54, 2004
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4OJ2
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1U0D
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![BU of 1u0d by Molmil](/molmil-images/mine/1u0d) | Y33H Mutant of Homing endonuclease I-CreI | Descriptor: | 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*CP*GP*C)-3', 5'-D(*GP*CP*GP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', DNA endonuclease I-CreI | Authors: | Sussman, D, Chadsey, M, Fauce, S, Engel, A, Bruett, A, Monnat, R, Stoddard, B.L, Seligman, L.M. | Deposit date: | 2004-07-13 | Release date: | 2004-11-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Isolation and characterization of new homing endonuclease specificities at individual target site positions. J.Mol.Biol., 342, 2004
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7JTI
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![BU of 7jti by Molmil](/molmil-images/mine/7jti) | Interphotoreceptor retinoid-binding protein (IRBP) in complex with a monoclonal antibody (F3F5 mAb5) | Descriptor: | Retinol-binding protein 3, mAb5 Fab heavy chain, mAb5 Fab light chain | Authors: | Sears, A.E, Albiez, S, Gulati, S, Wang, B, Kiser, P, Kovacik, L, Engel, A, Stahlberg, H, Palczewski, K. | Deposit date: | 2020-08-17 | Release date: | 2020-10-07 | Last modified: | 2020-12-16 | Method: | ELECTRON MICROSCOPY (7.4 Å) | Cite: | Single particle cryo-EM of the complex between interphotoreceptor retinoid-binding protein and a monoclonal antibody. Faseb J., 34, 2020
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1U0C
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![BU of 1u0c by Molmil](/molmil-images/mine/1u0c) | Y33C Mutant of Homing endonuclease I-CreI | Descriptor: | 5'-D(*CP*GP*TP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*AP*GP*C)-3', 5'-D(*GP*CP*TP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*AP*CP*G)-3', DNA endonuclease I-CreI, ... | Authors: | Sussman, D, Chadsey, M, Fauce, S, Engel, A, Bruett, A, Monnat, R, Stoddard, B.L, Seligman, L.M. | Deposit date: | 2004-07-13 | Release date: | 2004-11-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Isolation and characterization of new homing endonuclease specificities at individual target site positions. J.Mol.Biol., 342, 2004
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1H6I
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1EIK
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![BU of 1eik by Molmil](/molmil-images/mine/1eik) | Solution Structure of RNA Polymerase Subunit RPB5 from Methanobacterium Thermoautotrophicum | Descriptor: | RNA POLYMERASE SUBUNIT RPB5 | Authors: | Yee, A, Booth, V, Dharamsi, A, Engel, A, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2000-02-25 | Release date: | 2000-06-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the RNA polymerase subunit RPB5 from Methanobacterium thermoautotrophicum. Proc.Natl.Acad.Sci.USA, 97, 2000
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1FQY
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![BU of 1fqy by Molmil](/molmil-images/mine/1fqy) | STRUCTURE OF AQUAPORIN-1 AT 3.8 A RESOLUTION BY ELECTRON CRYSTALLOGRAPHY | Descriptor: | AQUAPORIN-1 | Authors: | Murata, K, Mitsuoka, K, Hirai, T, Walz, T, Agre, P, Heymann, J.B, Engel, A, Fujiyoshi, Y. | Deposit date: | 2000-09-07 | Release date: | 2000-10-18 | Last modified: | 2024-04-17 | Method: | ELECTRON CRYSTALLOGRAPHY (3.8 Å) | Cite: | Structural determinants of water permeation through aquaporin-1. Nature, 407, 2000
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6F7B
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![BU of 6f7b by Molmil](/molmil-images/mine/6f7b) | Crystal structure of the human Bub1 kinase domain in complex with BAY 1816032 | Descriptor: | 2-[3,5-bis(fluoranyl)-4-[[3-[5-methoxy-4-[(3-methoxypyridin-4-yl)amino]pyrimidin-2-yl]indazol-1-yl]methyl]phenoxy]ethanol, MAGNESIUM ION, Mitotic checkpoint serine/threonine-protein kinase BUB1 | Authors: | Holton, S.J, Siemeister, G, Mengel, A, Bone, W, Schroeder, J, Zitzmann-Kolbe, S, Briem, H, Fernandez-Montalvan, A, Prechtl, S, Moenning, U, von Ahsen, O, Johanssen, J, Cleve, A, Puetter, V, Hitchcock, M, von Nussbaum, F, Brands, M, Mumberg, D, Ziegelbauer, K. | Deposit date: | 2017-12-08 | Release date: | 2018-12-19 | Last modified: | 2021-05-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP InhibitorsIn VitroandIn Vivo. Clin.Cancer Res., 25, 2019
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2JBP
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![BU of 2jbp by Molmil](/molmil-images/mine/2jbp) | Protein kinase MK2 in complex with an inhibitor (crystal form-2, co- crystallization) | Descriptor: | 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE, MAP KINASE-ACTIVATED PROTEIN KINASE 2 | Authors: | Hillig, R.C, Eberspaecher, U, Monteclaro, F, Huber, M, Nguyen, D, Mengel, A, Muller-Tiemann, B, Egner, U. | Deposit date: | 2006-12-09 | Release date: | 2007-03-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Structural basis for a high affinity inhibitor bound to protein kinase MK2. J. Mol. Biol., 369, 2007
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2JBO
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![BU of 2jbo by Molmil](/molmil-images/mine/2jbo) | Protein kinase MK2 in complex with an inhibitor (crystal form-1, soaking) | Descriptor: | 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE, MAP KINASE-ACTIVATED PROTEIN KINASE 2, PHOSPHATE ION | Authors: | Hillig, R.C, Eberspaecher, U, Monteclaro, F, Huber, M, Nguyen, D, Mengel, A, Muller-Tiemann, B, Egner, U. | Deposit date: | 2006-12-09 | Release date: | 2007-03-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Basis for a High Affinity Inhibitor Bound to Protein Kinase Mk2. J.Mol.Biol., 369, 2007
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1Z9E
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![BU of 1z9e by Molmil](/molmil-images/mine/1z9e) | Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75 | Descriptor: | PC4 and SFRS1 interacting protein 2 | Authors: | Cherepanov, P, Sun, Z.-Y.J, Rahman, S, Maertens, G, Wagner, G, Engelman, A. | Deposit date: | 2005-04-01 | Release date: | 2005-05-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75 Nat.Struct.Mol.Biol., 12, 2005
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2B4J
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![BU of 2b4j by Molmil](/molmil-images/mine/2b4j) | Structural basis for the recognition between HIV-1 integrase and LEDGF/p75 | Descriptor: | GLYCEROL, Integrase (IN), PC4 and SFRS1 interacting protein, ... | Authors: | Cherepanov, P, Ambrosio, A.L, Rahman, S, Ellenberger, T, Engelman, A. | Deposit date: | 2005-09-24 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75 Proc.Natl.Acad.Sci.Usa, 102, 2005
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1ITG
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![BU of 1itg by Molmil](/molmil-images/mine/1itg) | CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HIV-1 INTEGRASE: SIMILARITY TO OTHER POLYNUCLEOTIDYL TRANSFERASES | Descriptor: | CACODYLATE ION, HIV-1 INTEGRASE | Authors: | Dyda, F, Hickman, A.B, Jenkins, T.M, Engelman, A, Craigie, R, Davies, D.R. | Deposit date: | 1994-11-21 | Release date: | 1995-05-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases. Science, 266, 1994
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6N1G
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6MZB
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![BU of 6mzb by Molmil](/molmil-images/mine/6mzb) | Cryo-EM structure of phosphodiesterase 6 | Descriptor: | GUANOSINE-3',5'-MONOPHOSPHATE, MAGNESIUM ION, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... | Authors: | Gulati, S, Palczewski, K. | Deposit date: | 2018-11-04 | Release date: | 2019-03-06 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases. Sci Adv, 5, 2019
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2RKO
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![BU of 2rko by Molmil](/molmil-images/mine/2rko) | Crystal Structure of the Vps4p-dimer | Descriptor: | Vacuolar protein sorting-associated protein 4 | Authors: | Hartmann, C, Gruetter, M.G. | Deposit date: | 2007-10-17 | Release date: | 2008-02-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Vacuolar protein sorting: two different functional states of the AAA-ATPase Vps4p J.Mol.Biol., 377, 2008
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7JTZ
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![BU of 7jtz by Molmil](/molmil-images/mine/7jtz) | Yeast Glo3 GAP domain | Descriptor: | ADP-ribosylation factor GTPase-activating protein GLO3, GLYCEROL, ZINC ION | Authors: | Xie, B, Jackson, L.P. | Deposit date: | 2020-08-18 | Release date: | 2021-03-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | The Glo3 GAP crystal structure supports the molecular niche model for ArfGAPs in COPI coats. Adv Biol Regul, 79, 2021
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2C32
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1GH8
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5D7U
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![BU of 5d7u by Molmil](/molmil-images/mine/5d7u) | Crystal structure of the C-terminal domain of MMTV integrase | Descriptor: | ISOPROPYL ALCOHOL, Pr160 | Authors: | Cook, N.J, Pye, V.E, Ballandras-Colas, A, Engelman, A, Cherepanov, P. | Deposit date: | 2015-08-14 | Release date: | 2016-02-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. Nature, 530, 2016
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4ID1
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5CZ2
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![BU of 5cz2 by Molmil](/molmil-images/mine/5cz2) | Crystal structure of a two-domain fragment of MMTV integrase | Descriptor: | MAGNESIUM ION, Pol polyprotein, ZINC ION | Authors: | Cook, N, Ballandras-Colas, A, Engelman, A, Cherepanov, P. | Deposit date: | 2015-07-31 | Release date: | 2016-02-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. Nature, 530, 2016
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4TSX
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5CZ1
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