6MZB
Cryo-EM structure of phosphodiesterase 6
Summary for 6MZB
Entry DOI | 10.2210/pdb6mzb/pdb |
EMDB information | 9297 |
Descriptor | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta, Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... (6 entities in total) |
Functional Keywords | gaf domain, phosphohydrolase, g protein-coupled receptor signaling, signaling protein |
Biological source | Bos taurus (Bovine) More |
Total number of polymer chains | 4 |
Total formula weight | 218149.73 |
Authors | Gulati, S.,Palczewski, K. (deposition date: 2018-11-04, release date: 2019-03-06, Last modification date: 2021-05-19) |
Primary citation | Gulati, S.,Palczewski, K.,Engel, A.,Stahlberg, H.,Kovacik, L. Cryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases. Sci Adv, 5:eaav4322-eaav4322, 2019 Cited by PubMed: 30820458DOI: 10.1126/sciadv.aav4322 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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