4YPI
| Structure of Ebola virus nucleoprotein N-terminal fragment bound to a peptide derived from Ebola VP35 | Descriptor: | Nucleoprotein, Polymerase cofactor VP35 | Authors: | Leung, D.W, Borek, D.M, Binning, J.M, Otwinowski, Z, Amarasinghe, G.K, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-03-13 | Release date: | 2015-04-08 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (3.71 Å) | Cite: | An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions. Cell Rep, 11, 2015
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6D00
| Calcarisporiella thermophila Hsp104 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Calcarisporiella thermophila Hsp104 | Authors: | Zhang, K, Pintilie, G. | Deposit date: | 2018-04-09 | Release date: | 2019-04-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events. Structure, 27, 2019
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6PMO
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4NWW
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4NWV
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1EEA
| Acetylcholinesterase | Descriptor: | PROTEIN (ACETYLCHOLINESTERASE) | Authors: | Raves, M.L, Giles, K, Schrag, J.D, Schmid, M.F, Phillips Jr, G.N, Wah, C, Howard, A.J, Silman, I, Sussman, J.L. | Deposit date: | 1999-01-26 | Release date: | 1999-02-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Quaternary Structure of Tetrameric Acetylcholinesterase Structure and Function of Cholinesterases and Related Proteins, 1998
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7TNQ
| The symmetry-released subpellicular microtubule map from detergent-extracted Toxoplasma cells | Descriptor: | Microtubule associated protein SPM1, PDI family protein, Tubulin alpha chain, ... | Authors: | Sun, S.Y, Pintilie, G.D, Chen, M. | Deposit date: | 2022-01-21 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (8.4 Å) | Cite: | Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures. Proc.Natl.Acad.Sci.USA, 119, 2022
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4CDI
| Crystal structure of AcrB-AcrZ complex | Descriptor: | ACRIFLAVINE RESISTANCE PROTEIN B, PREDICTED PROTEIN | Authors: | Du, D, James, N, Klimont, E, Luisi, B.F. | Deposit date: | 2013-10-31 | Release date: | 2014-04-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structure of the Acrab-Tolc Multidrug Efflux Pump. Nature, 509, 2014
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4C48
| Crystal structure of AcrB-AcrZ complex | Descriptor: | ACRIFLAVINE RESISTANCE PROTEIN B, DARPIN, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Du, D, James, N, Klimont, E, Luisi, B.F. | Deposit date: | 2013-09-02 | Release date: | 2014-04-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of the AcrAB-TolC multidrug efflux pump. Nature, 509, 2014
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8U2C
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8U28
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8U26
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6AZY
| Crystal structure of Hsp104 R328M/R757M mutant from Calcarisporiella thermophila | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Heat shock protein Hsp104 | Authors: | Michalska, K, Bigelow, L, Hatzos-Skintges, C, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2017-09-13 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events. Structure, 27, 2019
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6BG9
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6BO4
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6BO5
| TRPV2 ion channel in partially closed state | Descriptor: | Transient receptor potential cation channel subfamily V member 2 | Authors: | Dosey, T.L, Wang, Z. | Deposit date: | 2017-11-18 | Release date: | 2018-12-05 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of TRPV2 in distinct conformations provide insight into role of the pore turret. Nat.Struct.Mol.Biol., 26, 2019
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7M6B
| The Crystal Structure of Mcbe1 | Descriptor: | 1,2-ETHANEDIOL, S-ADENOSYL-L-HOMOCYSTEINE, S-ADENOSYLMETHIONINE, ... | Authors: | Alahuhta, P.M, Lunin, V.V. | Deposit date: | 2021-03-25 | Release date: | 2021-04-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Target highlights in CASP14: Analysis of models by structure providers. Proteins, 89, 2021
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7OC9
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5NC5
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5O66
| Asymmetric AcrABZ-TolC | Descriptor: | Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrA, Multidrug efflux pump subunit AcrB, ... | Authors: | Du, D, Luisi, B.F. | Deposit date: | 2017-06-05 | Release date: | 2017-06-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump. Elife, 6, 2017
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6TYL
| Crystal structure of mammalian Ric-8A:Galpha(i):nanobody complex | Descriptor: | Guanine nucleotide-binding protein G(i) subunit alpha-1, Nanobody A, Nanobody B, ... | Authors: | Mou, T.C, McClelland, L, Yates-Hansen, C, Sprang, S.R. | Deposit date: | 2019-08-09 | Release date: | 2020-03-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to G alpha i1. Nat Commun, 11, 2020
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6V3F
| Structure of NPC1-like intracellular cholesterol transporter 1 (NPC1L1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | Authors: | Huang, C.S, Yu, X, Min, X, Wang, Z. | Deposit date: | 2019-11-25 | Release date: | 2020-07-01 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition Sci Adv, 6, 2020
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6V4J
| Structure of TrkH-TrkA in complex with ATP | Descriptor: | Potassium uptake protein TrkA, Trk system potassium uptake protein TrkH | Authors: | Zhou, M, Zhang, H. | Deposit date: | 2019-11-27 | Release date: | 2020-02-12 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nat Commun, 11, 2020
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6V4L
| Structure of TrkH-TrkA in complex with ATPgammaS | Descriptor: | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Potassium uptake protein TrkA, Trk system potassium uptake protein TrkH | Authors: | Zhou, M, Zhang, H. | Deposit date: | 2019-11-27 | Release date: | 2020-02-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nat Commun, 11, 2020
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6V3H
| Structure of NPC1-like intracellular cholesterol transporter 1 (NPC1L1) in complex with an ezetimibe analog | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(2S,3R)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-1-(4-{3-[(methylsulfonyl)amino]prop-1-yn-1-yl}phenyl)-4-oxoazetidin-2-yl]phenyl beta-D-glucopyranosiduronic acid, ... | Authors: | Huang, C.S, Yu, X, Min, X, Wang, Z. | Deposit date: | 2019-11-25 | Release date: | 2020-07-01 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition Sci Adv, 6, 2020
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