6TYL

Crystal structure of mammalian Ric-8A:Galpha(i):nanobody complex

Summary for 6TYL

Entry DOI	10.2210/pdb6tyl/pdb
Descriptor	Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), Nanobody A, Nanobody B, ... (5 entities in total)
Functional Keywords	ric-8a, g protein, gef, signaling protein
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	10
Total formula weight	277975.80
Authors	Mou, T.C.,McClelland, L.,Yates-Hansen, C.,Sprang, S.R. (deposition date: 2019-08-09, release date: 2020-03-11, Last modification date: 2023-10-11)
Primary citation	McClelland, L.J.,Zhang, K.,Mou, T.C.,Johnston, J.,Yates-Hansen, C.,Li, S.,Thomas, C.J.,Doukov, T.I.,Triest, S.,Wohlkonig, A.,Tall, G.G.,Steyaert, J.,Chiu, W.,Sprang, S.R. Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to G alpha i1. Nat Commun, 11:1077-1077, 2020 Cited by PubMed: 32103024 DOI: 10.1038/s41467-020-14943-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation