6TYL
Crystal structure of mammalian Ric-8A:Galpha(i):nanobody complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, J (A, F) | Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) | polymer | 492 | 55836.9 | 2 | UniProt (B1H241) Pfam (PF10165) UniProt (by SIFTS) (Q80ZG1) | Rattus norvegicus (Rat) | Ric8a protein,Synembryn-A |
| 2 | B, C (C, H) | Nanobody A | polymer | 124 | 13609.9 | 2 | Lama glama | ||
| 3 | D, E (E, J) | Nanobody B | polymer | 131 | 14247.6 | 2 | Lama glama | ||
| 4 | F, G (D, I) | Nanobody C | polymer | 134 | 14894.4 | 2 | Lama glama | ||
| 5 | H, I (B, G) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40399.0 | 2 | UniProt (P10824) Pfam (PF00503) | Rattus norvegicus (Rat) | Adenylate cyclase-inhibiting G alpha protein |
Sequence modifications
A, F: 1 - 491 (UniProt: B1H241)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Phe 232 | Tyr 232 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 277975.8 | |
| All* | Total formula weight | 277975.8 |
