6V4L
Structure of TrkH-TrkA in complex with ATPgammaS
Summary for 6V4L
Entry DOI | 10.2210/pdb6v4l/pdb |
Descriptor | Trk system potassium uptake protein TrkH, Potassium uptake protein TrkA, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (3 entities in total) |
Functional Keywords | ion channel, transport protein |
Biological source | Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) More |
Total number of polymer chains | 4 |
Total formula weight | 208687.91 |
Authors | |
Primary citation | Zhang, H.,Pan, Y.,Hu, L.,Hudson, M.A.,Hofstetter, K.S.,Xu, Z.,Rong, M.,Wang, Z.,Prasad, B.V.V.,Lockless, S.W.,Chiu, W.,Zhou, M. TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nat Commun, 11:547-547, 2020 Cited by PubMed: 31992706DOI: 10.1038/s41467-019-14240-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.8 Å) |
Structure validation
Download full validation report