8U2C
Gaussian mixture model based single particle refinement - ABC transporter (inhibitor-bound ABCG2 from EMPIAR-10374)
Summary for 8U2C
| Entry DOI | 10.2210/pdb8u2c/pdb |
| Related | 6ETI |
| EMDB information | 3953 41845 |
| Descriptor | Broad substrate specificity ATP-binding cassette transporter ABCG2, 5D3 Fab light chain variable domain, 5D3 Fab heavy chain variable domain, ... (5 entities in total) |
| Functional Keywords | abc transporter, membrane protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 10 |
| Total formula weight | 331353.39 |
| Authors | Chen, M.,Pintilie, G. (deposition date: 2023-09-05, release date: 2023-11-15, Last modification date: 2024-01-24) |
| Primary citation | Chen, M.,Schmid, M.F.,Chiu, W. Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models. Nat.Methods, 21:37-40, 2024 Cited by PubMed: 37973972DOI: 10.1038/s41592-023-02082-9 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
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