8U2C
Gaussian mixture model based single particle refinement - ABC transporter (inhibitor-bound ABCG2 from EMPIAR-10374)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Broad substrate specificity ATP-binding cassette transporter ABCG2 | polymer | 655 | 72385.9 | 2 | UniProt (Q9UNQ0) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) | Homo sapiens (human) | ATP-binding cassette sub-family G member 2,Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter |
| 2 | C, E (C, E) | 5D3 Fab light chain variable domain | polymer | 214 | 23594.0 | 2 | Mus musculus | ||
| 3 | D, F (D, F) | 5D3 Fab heavy chain variable domain | polymer | 221 | 23843.6 | 2 | Mus musculus | ||
| 4 | G, I (I, J) | FAB heavy chain constant domain | polymer | 217 | 22986.8 | 2 | Homo sapiens | ||
| 5 | H, J (K, L) | Fab light chain constant domain | polymer | 210 | 22866.4 | 2 | Homo sapiens |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 331353.4 | |
| All* | Total formula weight | 331353.4 |
