6AZY

Crystal structure of Hsp104 R328M/R757M mutant from Calcarisporiella thermophila

Summary for 6AZY

Entry DOI	10.2210/pdb6azy/pdb
Descriptor	Heat shock protein Hsp104, ADENOSINE-5'-DIPHOSPHATE (2 entities in total)
Functional Keywords	disaggregase, aaa+ atpase, structural genomics, psi-biology, midwest center for structural genomics, mcsg, chaperone
Biological source	Calcarisporiella thermophila
Total number of polymer chains	1
Total formula weight	99914.70
Authors	Michalska, K.,Bigelow, L.,Hatzos-Skintges, C.,Jedrzejczak, R.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2017-09-13, release date: 2018-10-03, Last modification date: 2023-10-04)
Primary citation	Michalska, K.,Zhang, K.,March, Z.M.,Hatzos-Skintges, C.,Pintilie, G.,Bigelow, L.,Castellano, L.M.,Miles, L.J.,Jackrel, M.E.,Chuang, E.,Jedrzejczak, R.,Shorter, J.,Chiu, W.,Joachimiak, A. Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events. Structure, 27:449-463.e7, 2019 Cited by PubMed: 30595457 DOI: 10.1016/j.str.2018.11.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation