8HDG
 
 | | Small peptide enhances the binding of nutline-3a to MdmX | | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, Uncharacterized protein DKFZp686B01123 | | Authors: | Cheng, X.Y, Huang, Y, Wei, Q.Y, Huang, J.J, Peng, Y.W, Su, Z.D. | | Deposit date: | 2022-11-04 | | Release date: | 2022-11-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Small peptide enhances the binding of nutline-3a to MdmX
To Be Published
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8IA5
 | | Small peptide enhances the binding of nutline-3a to N-terminal domain of MdmX | | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, 9-mer peptide, ... | | Authors: | Cheng, X.Y, Wei, Q.Y, Huang, Y, Su, Z.D. | | Deposit date: | 2023-02-07 | | Release date: | 2023-02-22 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Small peptide enhances the binding of nutline-3a to N-terminal domain of MdmX
To Be Published
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5ZXF
 | | The 1.25A Crystal structure of His6-tagged Mdm2 in complex with nutlin-3a | | Descriptor: | 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, E3 ubiquitin-protein ligase Mdm2 | | Authors: | Cheng, X.Y, Su, Z.D, Pi, N, Cao, C.Z, Zhao, Z.T, Zhou, J.J, Chen, R, Kuang, Z.K, Huang, Y.Q. | | Deposit date: | 2018-05-19 | | Release date: | 2018-08-22 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | The 1.25A Crystal structure of His6-tagged Mdm2 in complex with nutlin-3a
To Be Published
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5ZUT
 | | Crystal Structure of Yeast PCNA in Complex with N24 Peptide | | Descriptor: | N24, Proliferating cell nuclear antigen | | Authors: | Cheng, X.Y, Kuang, X.L, Zhou, Y, Xia, X.M, SU, Z.D. | | Deposit date: | 2018-05-08 | | Release date: | 2018-05-30 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.82 Å) | | Cite: | Crystal Structure of Yeast PCNA in Complex with N24 Peptide
To Be Published
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7C44
 | | Crystal structure of the p53-binding domain of human MdmX protein in complex with Nutlin3a | | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, Protein Mdm4 | | Authors: | Cheng, X.Y, Zhang, B.L, Kuang, Z.K, Yang, J, Li, Z.C, Yu, J.P, Zhao, Z.T, Cao, C.Z, Su, Z.D. | | Deposit date: | 2020-05-15 | | Release date: | 2020-06-17 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of the p53-binding domain of human MdmX protein in complex with Nutlin3a
To Be Published
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6KUW
 | | Crystal structure of human alpha2C adrenergic G protein-coupled receptor. | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (8~{a}~{R},12~{a}~{S},13~{a}~{R})-12-ethylsulfonyl-3-methoxy-5,6,8,8~{a},9,10,11,12~{a},13,13~{a}-decahydroisoquinolino[2,1-g][1,6]naphthyridine, Alpha-2C adrenergic receptor, ... | | Authors: | Chen, X.Y, Wu, L.J, Wu, D, Zhong, G.S. | | Deposit date: | 2019-09-02 | | Release date: | 2019-12-04 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of human alpha2C adrenergic G protein-coupled receptor.
To Be Published
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7EL4
 | | The crystal structure of p53p peptide fragment in complex with the N-terminal domain of MdmX | | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Cellular tumor antigen p53,Protein Mdm4, MAGNESIUM ION | | Authors: | Cheng, X.Y, Zhang, B.L, Li, Z.C, Kuang, Z.K, Su, Z.D. | | Deposit date: | 2021-04-08 | | Release date: | 2021-06-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | The crystal structure of the N-terminal domain of MdmX in complex with p53p peptide fragment
To Be Published
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7XPM
 | | Ancestral ADH WT | | Descriptor: | 1,2-ETHANEDIOL, A64 | | Authors: | Chen, X.Y, Xu, G.C, Ni, Y. | | Deposit date: | 2022-05-04 | | Release date: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal structure of a versatile ancestral ADH with high activity and thermostability
To Be Published
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5Z3R
 | | Crystal Structure of Delta 5-3-Ketosteroid Isomerase from Mycobacterium sp. | | Descriptor: | Steroid delta-isomerase | | Authors: | Cheng, X.Y, Peng, F, Yang, F, Huang, Y.Q, Su, Z.D. | | Deposit date: | 2018-01-08 | | Release date: | 2018-01-31 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Structure-based reconstruction of a Mycobacterium hypothetical protein into an active Delta5-3-ketosteroid isomerase.
Biochim Biophys Acta Proteins Proteom, 1867, 2019
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4BZ1
 | | Structure of dengue virus EDIII in complex with Fab 3e31 | | Descriptor: | CHLORIDE ION, ENVELOPE PROTEIN, FAB 3E31 HEAVY CHAIN, ... | | Authors: | Li, J, Watterson, D, Chang, C.W, Li, X.Q, Ericsson, D.J, Qiu, L.W, Cai, J.P, Chen, J, Fry, S.R, Cooper, M.A, Che, X.Y, Young, P.R, Kobe, B. | | Deposit date: | 2013-07-23 | | Release date: | 2014-08-13 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure of Dengue Virus Ediii in Complex with Fab 3E31
To be Published
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4BZ2
 | | Structure of dengue virus EDIII in complex with Fab 2D73 | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ENVELOPE PROTEIN, ... | | Authors: | Li, J, Watterson, D, Chang, C.W, Li, X.Q, Ericsson, D.J, Qiu, L.W, Cai, J.P, Chen, J, Fry, S.R, Cooper, M.A, Che, X.Y, Young, P.R, Kobe, B. | | Deposit date: | 2013-07-23 | | Release date: | 2014-08-13 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structure of Dengue Virus Ediii in Complex with Fab 2D73
To be Published
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8KGZ
 | | Crystal structure of single-chain Fv antibody against antigen peptide from SARS-CoV2 S-spike protein | | Descriptor: | Thioredoxin 1,scFv | | Authors: | Ma, Q.Q, Zhang, B.L, Cheng, X.Y, Huang, Y.Q, Su, Z.D. | | Deposit date: | 2023-08-20 | | Release date: | 2023-11-08 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Crystal structure of sheep scFv antibody against an antigen peptide of SARS-CoV2 S-spike protein
To Be Published
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8JBZ
 | | Crystal structure of 3-ketosteroid delta1-dehydrogenase from Rhodococcus erythropolis SQ1 in complex with 4-androstadiene-3,17- dione | | Descriptor: | 3-ketosteroid dehydrogenase, 4-ANDROSTENE-3-17-DIONE, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Hu, Y.L, Li, X, Cheng, X.Y, Song, S.K, Su, Z.D. | | Deposit date: | 2023-05-10 | | Release date: | 2023-05-31 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.079 Å) | | Cite: | Crystal structure of 3-ketosteroid delta1-dehydrogenase from Rhodococcus erythropolis SQ1 in complex with 4-androstadiene-3,17- dione
To Be Published
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5Z02
 | | Crystal structure of HIS6-tagged Mdm2 with nutlin-3a | | Descriptor: | 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, E3 ubiquitin-protein ligase Mdm2 | | Authors: | Su, Z.D, Cheng, X.Y, Chen, R, Pi, N. | | Deposit date: | 2017-12-18 | | Release date: | 2018-01-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Crystal structure of HIS6-tagged Mdm2 with nutlin-3a
to be published
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8XML
 | | Cryo-EM structure of the Apo CCR8-Gi complex | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | Authors: | Peng, Q, Jiang, H.H, Cheng, X.Y, Li, J, Zhang, J. | | Deposit date: | 2023-12-27 | | Release date: | 2025-01-01 | | Method: | ELECTRON MICROSCOPY (2.58 Å) | | Cite: | Cryo-EM structure of the Apo CCR8-Gi complex
To Be Published
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8Y01
 | | Cryo-EM structure of Medium-wave-sensitive opsin 1 | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | Authors: | Peng, Q, Jiang, H.H, Cheng, X.Y, Li, J, Zhang, J. | | Deposit date: | 2024-01-21 | | Release date: | 2025-02-12 | | Method: | ELECTRON MICROSCOPY (2.48 Å) | | Cite: | Cryo-EM structure of Medium-wave-sensitive opsin 1
To Be Published
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7C3Q
 | | Human MdmX protein in complex with Nutlin3a | | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Su, Z.D, Cheng, X.Y, Zhang, B.L, Kuang, Z.K, Yang, J, Li, Z.C, Yu, J.P, Zhao, Z.T, Cao, C.Z. | | Deposit date: | 2020-05-13 | | Release date: | 2020-06-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.801 Å) | | Cite: | Human MdmX protein in complex with Nutlin3a
To Be Published
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7C3Y
 | | Crystal structure of the N-terminal domain of human MdmX protein in complex with Nutlin3a | | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, Protein Mdm4 | | Authors: | Su, Z.D, Cheng, X.Y, Zhang, B.L, Kuang, Z.K, Yang, J, Li, Z.C, Yu, J.P, Zhao, Z.T, Cao, C.Z. | | Deposit date: | 2020-05-14 | | Release date: | 2020-06-17 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.632 Å) | | Cite: | Crystal structure of the N-terminal domain of human MdmX protein in complex with Nutlin3a
To Be Published
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6IHG
 | | N terminal domain of Mycobacterium avium complex Lon protease | | Descriptor: | Lon protease | | Authors: | Chen, X.Y, Zhang, S.J, Bi, F.K, Guo, C.Y, Yao, H.W, Lin, D.H. | | Deposit date: | 2018-09-29 | | Release date: | 2019-08-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.397 Å) | | Cite: | Crystal structure of the N domain of Lon protease from Mycobacterium avium complex.
Protein Sci., 28, 2019
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4MHH
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4MHI
 | | Crystal structure of a H5N1 influenza virus hemagglutinin from A/goose/Guangdong/1/96 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | | Authors: | Zhu, X, Wilson, I.A. | | Deposit date: | 2013-08-29 | | Release date: | 2013-10-02 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.595 Å) | | Cite: | A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
J.Virol., 87, 2013
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4MHJ
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8KCN
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8JUH
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6VBK
 | | Crystal structure of N-terminal domain of Mycobacterium tuberculosis complex Lon protease | | Descriptor: | GLYCEROL, Lon211 | | Authors: | Bi, F.K, Chen, C, Chen, X.Y, Guo, C.Y, Lin, D.H. | | Deposit date: | 2019-12-19 | | Release date: | 2020-12-23 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the N domain of Lon protease from Mycobacterium avium complex.
Protein Sci., 28, 2019
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