8HDG

Small peptide enhances the binding of nutline-3a to MdmX

Summary for 8HDG

• Entry DOI: 10.2210/pdb8hdg/pdb
• Descriptor: Uncharacterized protein DKFZp686B01123, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, ... (4 entities in total)
• Functional Keywords: mdmx, p53, nutlin-3a, enhancement, oncoprotein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 54321.68

Authors

Cheng, X.Y.,Huang, Y.,Wei, Q.Y.,Huang, J.J.,Peng, Y.W.,Su, Z.D. (deposition date: 2022-11-04, release date: 2022-11-30, Last modification date: 2023-11-29)

• Primary citation: Cheng, X.Y.,Huang, Y.,Wei, Q.Y.,Huang, J.J.,Peng, Y.W.,Su, Z.D.; Small peptide enhances the binding of nutline-3a to MdmX; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.73 Å)