8IA5
Small peptide enhances the binding of nutline-3a to N-terminal domain of MdmX
Summary for 8IA5
Entry DOI | 10.2210/pdb8ia5/pdb |
Descriptor | Protein Mdm4, 9-mer peptide, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, ... (5 entities in total) |
Functional Keywords | mdmx, p53, nutlin-3a, enhancement, oncoprotein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 12191.95 |
Authors | Cheng, X.Y.,Wei, Q.Y.,Huang, Y.,Su, Z.D. (deposition date: 2023-02-07, release date: 2023-02-22, Last modification date: 2024-05-29) |
Primary citation | Cheng, X.Y.,Wei, Q.Y.,Huang, Y.,Su, Z.D. Small peptide enhances the binding of nutline-3a to N-terminal domain of MdmX To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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