8IA5
Small peptide enhances the binding of nutline-3a to N-terminal domain of MdmX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Protein Mdm4 | polymer | 90 | 10248.0 | 1 | UniProt (O15151) In PDB | Homo sapiens (human) | Double minute 4 protein,Mdm2-like p53-binding protein,Protein Mdmx,p53-binding protein Mdm4 |
| 2 | B | 9-mer peptide | polymer | 9 | 1098.2 | 1 | synthetic construct | ||
| 3 | A | 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one | non-polymer | 581.5 | 1 | Chemie (NUT) | |||
| 4 | A | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE | non-polymer | 264.3 | 1 | Chemie (O4B) | |||
| 5 | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence modifications
A: 22 - 110 (UniProt: O15151)
| PDB | External Database | Details |
|---|---|---|
| Ser 21 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 11346.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 845.8 | |
| All* | Total formula weight | 12191.9 |
