7C44
Crystal structure of the p53-binding domain of human MdmX protein in complex with Nutlin3a
Summary for 7C44
Entry DOI | 10.2210/pdb7c44/pdb |
Descriptor | Protein Mdm4, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, ... (4 entities in total) |
Functional Keywords | mdmx, nutlin-3a, oncoprotein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 11888.59 |
Authors | Cheng, X.Y.,Zhang, B.L.,Kuang, Z.K.,Yang, J.,Li, Z.C.,Yu, J.P.,Zhao, Z.T.,Cao, C.Z.,Su, Z.D. (deposition date: 2020-05-15, release date: 2020-06-17, Last modification date: 2023-11-29) |
Primary citation | Cheng, X.Y.,Zhang, B.L.,Kuang, Z.K.,Yang, J.,Li, Z.C.,Yu, J.P.,Zhao, Z.T.,Cao, C.Z.,Su, Z.D. Crystal structure of the p53-binding domain of human MdmX protein in complex with Nutlin3a To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
Download full validation report