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7C44

Crystal structure of the p53-binding domain of human MdmX protein in complex with Nutlin3a

Summary for 7C44
Entry DOI10.2210/pdb7c44/pdb
DescriptorProtein Mdm4, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, ... (4 entities in total)
Functional Keywordsmdmx, nutlin-3a, oncoprotein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight11888.59
Authors
Cheng, X.Y.,Zhang, B.L.,Kuang, Z.K.,Yang, J.,Li, Z.C.,Yu, J.P.,Zhao, Z.T.,Cao, C.Z.,Su, Z.D. (deposition date: 2020-05-15, release date: 2020-06-17, Last modification date: 2023-11-29)
Primary citationCheng, X.Y.,Zhang, B.L.,Kuang, Z.K.,Yang, J.,Li, Z.C.,Yu, J.P.,Zhao, Z.T.,Cao, C.Z.,Su, Z.D.
Crystal structure of the p53-binding domain of human MdmX protein in complex with Nutlin3a
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.65 Å)
Structure validation

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