7C44

Crystal structure of the p53-binding domain of human MdmX protein in complex with Nutlin3a

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0043066	biological_process	negative regulation of apoptotic process
A	0051726	biological_process	regulation of cell cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue NUT A 201

Chain	Residue
A	LEU13
A	VAL91
A	PRO94
A	LEU97
A	TYR98
A	HOH309
A	GLU14
A	TYR17
A	MET52
A	GLY56
A	ILE59
A	MET60
A	GLN70
A	HIS71

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site_id	AC2
Number of Residues	5
Details	binding site for residue O4B A 202

Chain	Residue
A	GLN22
A	LYS34
A	GLN63
A	TYR65
A	TYR74

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