4I85
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![BU of 4i85 by Molmil](/molmil-images/mine/4i85) | Crystal structure of transthyretin in complex with CHF5074 at neutral pH | Descriptor: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin | Authors: | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | Deposit date: | 2012-12-03 | Release date: | 2013-06-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors. Febs Lett., 587, 2013
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1TYR
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![BU of 1tyr by Molmil](/molmil-images/mine/1tyr) | TRANSTHYRETIN COMPLEX WITH RETINOIC ACID | Descriptor: | (9cis)-retinoic acid, TRANSTHYRETIN | Authors: | Zanotti, G, D'Acunto, M.R, Malpeli, G, Folli, C, Berni, R. | Deposit date: | 1995-05-12 | Release date: | 1995-09-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the transthyretin--retinoic-acid complex Eur.J.Biochem., 234, 1995
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4I89
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![BU of 4i89 by Molmil](/molmil-images/mine/4i89) | Crystal structure of transthyretin in complex with diflunisal at acidic pH | Descriptor: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin | Authors: | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | Deposit date: | 2012-12-03 | Release date: | 2013-06-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors. Febs Lett., 587, 2013
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4I87
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![BU of 4i87 by Molmil](/molmil-images/mine/4i87) | Crystal structure of TTR variant I84S in complex with CHF5074 at acidic pH | Descriptor: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin | Authors: | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | Deposit date: | 2012-12-03 | Release date: | 2013-06-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors. Febs Lett., 587, 2013
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3Q1E
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![BU of 3q1e by Molmil](/molmil-images/mine/3q1e) | Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase in complex with T4 | Descriptor: | 3,5,3',5'-TETRAIODO-L-THYRONINE, 5-hydroxyisourate hydrolase | Authors: | Cendron, L, Ramazzina, I, Percudani, R, Zanotti, G, Berni, R. | Deposit date: | 2010-12-17 | Release date: | 2011-05-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign. J.Mol.Biol., 409, 2011
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1FEM
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![BU of 1fem by Molmil](/molmil-images/mine/1fem) | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | Descriptor: | RETINOIC ACID, RETINOL BINDING PROTEIN | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | Deposit date: | 1994-08-29 | Release date: | 1994-11-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein. J.Biol.Chem., 269, 1994
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1FEN
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![BU of 1fen by Molmil](/molmil-images/mine/1fen) | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | Descriptor: | ALL-TRANS AXEROPHTHENE, RETINOL BINDING PROTEIN | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | Deposit date: | 1994-08-29 | Release date: | 1994-11-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein. J.Biol.Chem., 269, 1994
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1FEL
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![BU of 1fel by Molmil](/molmil-images/mine/1fel) | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | Descriptor: | N-(4-HYDROXYPHENYL)ALL-TRANS RETINAMIDE, RETINOL BINDING PROTEIN | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | Deposit date: | 1994-08-29 | Release date: | 1994-11-01 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein. J.Biol.Chem., 269, 1994
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1IIU
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![BU of 1iiu by Molmil](/molmil-images/mine/1iiu) | |
3IWV
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![BU of 3iwv by Molmil](/molmil-images/mine/3iwv) | Crystal structure of Y116T mutant of 5-HYDROXYISOURATE HYDROLASE (TRP) | Descriptor: | 5-hydroxyisourate hydrolase | Authors: | Cendron, L, Ramazzina, I, Berni, R, Percudani, R, Zanotti, G. | Deposit date: | 2009-09-03 | Release date: | 2010-09-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign. J.Mol.Biol., 409, 2011
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3IWU
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![BU of 3iwu by Molmil](/molmil-images/mine/3iwu) | Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase | Descriptor: | 5-hydroxyisourate hydrolase | Authors: | Cendron, L, Ramazzina, I, Berni, R, Percudani, R, Zanotti, G. | Deposit date: | 2009-09-03 | Release date: | 2010-09-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign. J.Mol.Biol., 409, 2011
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1ERB
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![BU of 1erb by Molmil](/molmil-images/mine/1erb) | |
6SUG
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![BU of 6sug by Molmil](/molmil-images/mine/6sug) | Crystal structure of transthyretin in complex with 3-deoxytolcapone, a tolcapone analogue | Descriptor: | 3-deoxytolcapone, Transthyretin | Authors: | Loconte, V, Cianci, M, Menozzi, I, Sbravati, D, Sansone, F, Casnati, A, Berni, R. | Deposit date: | 2019-09-14 | Release date: | 2020-08-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Interactions of tolcapone analogues as stabilizers of the amyloidogenic protein transthyretin. Bioorg.Chem., 103, 2020
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2B5S
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![BU of 2b5s by Molmil](/molmil-images/mine/2b5s) | Crystal structure of peach Pru p3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens | Descriptor: | HEPTANE, LAURIC ACID, Non-specific lipid transfer protein, ... | Authors: | Pasquato, N, Berni, R, Folli, C, Folloni, S, Cianci, M, Pantano, S, Helliwell, R.J, Zanotti, G. | Deposit date: | 2005-09-29 | Release date: | 2005-11-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal Structure of Peach Pru p 3, the Prototypic Member of the Family of Plant Non-specific Lipid Transfer Protein Pan-allergens J.Mol.Biol., 356, 2006
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1BOI
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![BU of 1boi by Molmil](/molmil-images/mine/1boi) | N-TERMINALLY TRUNCATED RHODANESE | Descriptor: | RHODANESE | Authors: | Gliubich, F, Berni, R, Cianci, M, Trevino, R.J, Horowitz, P.M, Zanotti, G. | Deposit date: | 1998-08-04 | Release date: | 1999-04-27 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | NH2-terminal sequence truncation decreases the stability of bovine rhodanese, minimally perturbs its crystal structure, and enhances interaction with GroEL under native conditions. J.Biol.Chem., 274, 1999
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1BOH
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![BU of 1boh by Molmil](/molmil-images/mine/1boh) | SULFUR-SUBSTITUTED RHODANESE (ORTHORHOMBIC FORM) | Descriptor: | RHODANESE | Authors: | Gliubich, F, Berni, R, Cianci, M, Trevino, R.J, Horowitz, P.M, Zanotti, G. | Deposit date: | 1998-08-04 | Release date: | 1999-04-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | NH2-terminal sequence truncation decreases the stability of bovine rhodanese, minimally perturbs its crystal structure, and enhances interaction with GroEL under native conditions. J.Biol.Chem., 274, 1999
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4ALO
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![BU of 4alo by Molmil](/molmil-images/mine/4alo) | STRUCTURE AND PROPERTIES OF H1 CRUSTACYANIN FROM LOBSTER HOMARUS AMERICANUS | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, H1 APOCRUSTACYANIN, SODIUM ION, ... | Authors: | Ferrari, M, Folli, C, Pincolini, E, Mcclintock, T.S, Roessle, M, Berni, R, Cianci, M. | Deposit date: | 2012-03-05 | Release date: | 2012-08-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Structural Characterization of Recombinant Crustacyanin Subunits from the Lobster Homarus Americanus. Acta Crystallogr.,Sect.F, 68, 2012
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2ALG
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![BU of 2alg by Molmil](/molmil-images/mine/2alg) | Crystal structure of peach Pru p3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens | Descriptor: | HEPTANE, HEXAETHYLENE GLYCOL, LAURIC ACID, ... | Authors: | Pasquato, N, Berni, R, Folli, C, Folloni, S, Cianci, M, Pantano, S, Helliwell, J, Zanotti, G. | Deposit date: | 2005-08-05 | Release date: | 2005-11-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Peach Pru p 3, the Prototypic Member of the Family of Plant Non-specific Lipid Transfer Protein Pan-allergens J.Mol.Biol., 356, 2006
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2H1X
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![BU of 2h1x by Molmil](/molmil-images/mine/2h1x) | Crystal structure of 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) | Descriptor: | 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) | Authors: | Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R. | Deposit date: | 2006-05-17 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter. J.Mol.Biol., 363, 2006
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2H6U
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![BU of 2h6u by Molmil](/molmil-images/mine/2h6u) | Crystal structure of 5-hydroxyisourate hydrolase (formerly known as TRP, transthyretin related protein) | Descriptor: | 5-HYDROXYISOURATE HYDROLASE (FORMERLY KNOWN AS TRP, TRANSTHYRETIN RELATED PROTEIN) | Authors: | Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R. | Deposit date: | 2006-06-01 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter. J.Mol.Biol., 363, 2006
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2O70
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![BU of 2o70 by Molmil](/molmil-images/mine/2o70) | Structure of OHCU decarboxylase from zebrafish | Descriptor: | OHCU decarboxylase | Authors: | Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G. | Deposit date: | 2006-12-09 | Release date: | 2007-04-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation. J.Biol.Chem., 282, 2007
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4WO0
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![BU of 4wo0 by Molmil](/molmil-images/mine/4wo0) | Crystal structure of transthyretin in complex with apigenin | Descriptor: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Transthyretin | Authors: | Zanotti, G, Cianci, M, Folli, C, Berni, R. | Deposit date: | 2014-10-15 | Release date: | 2015-08-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.339 Å) | Cite: | Structural evidence for asymmetric ligand binding to transthyretin. Acta Crystallogr.,Sect.D, 71, 2015
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4WNJ
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![BU of 4wnj by Molmil](/molmil-images/mine/4wnj) | Crystal structure of Transthyretin-quercetin complex | Descriptor: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, DIMETHYL SULFOXIDE, Transthyretin | Authors: | Zanotti, G, Cianci, M, Berni, R, Folli, C. | Deposit date: | 2014-10-13 | Release date: | 2015-08-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.398 Å) | Cite: | Structural evidence for asymmetric ligand binding to transthyretin. Acta Crystallogr.,Sect.D, 71, 2015
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4WNS
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![BU of 4wns by Molmil](/molmil-images/mine/4wns) | Crystal structure of Transthyretin complexed with pterostilbene | Descriptor: | DIMETHYL SULFOXIDE, Pterostilbene, SULFATE ION, ... | Authors: | Zanotti, G, Cianci, M, Folli, C, Berni, R. | Deposit date: | 2014-10-14 | Release date: | 2015-08-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.399 Å) | Cite: | Structural evidence for asymmetric ligand binding to transthyretin. Acta Crystallogr.,Sect.D, 71, 2015
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1AQB
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![BU of 1aqb by Molmil](/molmil-images/mine/1aqb) | RETINOL-BINDING PROTEIN (RBP) FROM PIG PLASMA | Descriptor: | CADMIUM ION, RETINOL, RETINOL-BINDING PROTEIN | Authors: | Zanotti, G, Panzalorto, M, Marcato, A, Malpeli, G, Folli, C, Berni, R. | Deposit date: | 1997-07-28 | Release date: | 1998-01-28 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure of pig plasma retinol-binding protein at 1.65 A resolution. Acta Crystallogr.,Sect.D, 54, 1998
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