6WXL
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6C6Y
| Crystal structure of Middle-East Respiratory Syndrome (MERS) coronavirus neutralizing antibody JC57-14 isolated from a vaccinated rhesus macaque in complex with MERS Receptor Binding Domain | 分子名称: | JC57-14 Heavy chain, JC57-14 Light chain, SULFATE ION, ... | 著者 | Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D. | 登録日 | 2018-01-19 | 公開日 | 2018-03-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | 主引用文献 | Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape. J. Virol., 92, 2018
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6C6X
| Crystal structure of Middle-East Respiratory Syndrome (MERS) coronavirus neutralizing antibody JC57-14 isolated from a vaccinated rhesus macaque. | 分子名称: | JC57-14 Heavy chain, JC57-14 Light chain | 著者 | Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D. | 登録日 | 2018-01-19 | 公開日 | 2018-02-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape. J. Virol., 92, 2018
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6C6Z
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5JOF
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5F9O
| Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235.09 in complex with HIV-1 clade A/E 93TH057 gp120 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CH235.09 Light chain, ... | 著者 | Joyce, M.G, Mascola, J.R, Kwong, P.D. | 登録日 | 2015-12-10 | 公開日 | 2016-03-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody. Cell, 165, 2016
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6UBI
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6UDA
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6UCE
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6UCF
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4MMS
| Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 5.5 | 分子名称: | Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, SULFATE ION | 著者 | Mclellan, J.S, Joyce, M.G, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. | 登録日 | 2013-09-09 | 公開日 | 2013-11-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | 主引用文献 | Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
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4MMR
| Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 9.5 | 分子名称: | Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2 | 著者 | Stewart-Jones, G.B.E, McLellan, J.S, Joyce, M.G, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. | 登録日 | 2013-09-09 | 公開日 | 2013-11-20 | 最終更新日 | 2021-06-02 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
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4MMV
| Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1-TriC at pH 9.5 | 分子名称: | Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2 | 著者 | Stewart-Jones, G.B.E, McLellan, J.S, Joyce, M.G, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. | 登録日 | 2013-09-09 | 公開日 | 2013-11-20 | 最終更新日 | 2021-06-02 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
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4MMU
| Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 5.5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, ... | 著者 | Joyce, M.G, Mclellan, J.S, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. | 登録日 | 2013-09-09 | 公開日 | 2013-11-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
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4MMT
| Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 9.5 | 分子名称: | Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2 | 著者 | Joyce, M.G, Mclellan, J.S, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. | 登録日 | 2013-09-09 | 公開日 | 2013-11-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
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4MMQ
| Crystal Structure of Prefusion-stabilized RSV F Variant DS | 分子名称: | Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, SULFATE ION | 著者 | Mclellan, J.S, Joyce, M.G, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. | 登録日 | 2013-09-09 | 公開日 | 2013-11-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.253 Å) | 主引用文献 | Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
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7SG4
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7L2C
| Crystallographic structure of neutralizing antibody 2-51 in complex with SARS-CoV-2 spike N-terminal domain (NTD) | 分子名称: | 2-51 heavy chain, 2-51 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Cerutti, G, Reddem, E.R, Shapiro, L. | 登録日 | 2020-12-16 | 公開日 | 2021-02-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. Cell Host Microbe, 29, 2021
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7L2E
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7L2F
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7L2D
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7L0L
| Cryo-EM structure of the VRC316 clinical trial, vaccine-elicited, human antibody 316-310-1B11 in complex with an H2 CAN05 HA trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 316-310-1B11 Heavy Chain, 316-310-1B11 Light Chain, ... | 著者 | Gorman, J, Kwong, P.D. | 登録日 | 2020-12-11 | 公開日 | 2021-11-03 | 最終更新日 | 2022-03-09 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination. Nat Med, 28, 2022
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8D21
| Cryo-EM structure of the VRC321 clinical trial, vaccine-elicited, human antibody 1B06 in complex with a stabilized NC99 HA trimer | 分子名称: | 1B06 Heavy Chain, 1B06 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gorman, J, Kwong, P.D. | 登録日 | 2022-05-27 | 公開日 | 2023-04-12 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | An influenza H1 hemagglutinin stem-only immunogen elicits a broadly cross-reactive B cell response in humans. Sci Transl Med, 15, 2023
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7LL2
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7LL1
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