7LL1

Cryo-EM structure of BG505 DS-SOSIP in complex with glycan276-dependent broadly neutralizing antibody VRC40.01 Fab

Summary for 7LL1

• Entry DOI: 10.2210/pdb7ll1/pdb
• Related: 7LL2 7LLK
• EMDB information: 23411
• Descriptor: Envelope glycoprotein gp120, Envelope glycoprotein gp41, VRC40.01 Fab Heavy chain, ... (7 entities in total)
• Functional Keywords: bg505 ds-sosip, glycan276-dependent, glycan276, broadly neutralizing antibody, vrc40.01 fab, hiv- 1 env, immune system, immune system-viral protein complex, immune system/viral protein
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 12
• Total formula weight: 376005.52

Authors

Manne, K.,Acharya, P. (deposition date: 2021-02-03, release date: 2021-03-17, Last modification date: 2021-11-17)

• Primary citation: Cottrell, C.A.,Manne, K.,Kong, R.,Wang, S.,Zhou, T.,Chuang, G.Y.,Edwards, R.J.,Henderson, R.,Janowska, K.,Kopp, M.,Lin, B.C.,Louder, M.K.,Olia, A.S.,Rawi, R.,Shen, C.H.,Taft, J.D.,Torres, J.L.,Wu, N.R.,Zhang, B.,Doria-Rose, N.A.,Cohen, M.S.,Haynes, B.F.,Shapiro, L.,Ward, A.B.,Acharya, P.,Mascola, J.R.,Kwong, P.D.; Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies.; Cell Rep, 37:109922-109922, 2021; PubMed: 34731616; DOI: 10.1016/j.celrep.2021.109922

Experimental method

ELECTRON MICROSCOPY (3.73 Å)