6C6X
Crystal structure of Middle-East Respiratory Syndrome (MERS) coronavirus neutralizing antibody JC57-14 isolated from a vaccinated rhesus macaque.
Summary for 6C6X
Entry DOI | 10.2210/pdb6c6x/pdb |
Descriptor | JC57-14 Heavy chain, JC57-14 Light chain (3 entities in total) |
Functional Keywords | antibody, neutralizing, vaccine, immune system |
Biological source | Macaca mulatta (Rhesus monkey) More |
Total number of polymer chains | 8 |
Total formula weight | 189181.44 |
Authors | Joyce, M.G.,Mascola, J.R.,Graham, B.S.,Kwong, P.D. (deposition date: 2018-01-19, release date: 2018-02-28, Last modification date: 2023-10-04) |
Primary citation | Wang, L.,Shi, W.,Chappell, J.D.,Joyce, M.G.,Zhang, Y.,Kanekiyo, M.,Becker, M.M.,van Doremalen, N.,Fischer, R.,Wang, N.,Corbett, K.S.,Choe, M.,Mason, R.D.,Van Galen, J.G.,Zhou, T.,Saunders, K.O.,Tatti, K.M.,Haynes, L.M.,Kwong, P.D.,Modjarrad, K.,Kong, W.P.,McLellan, J.S.,Denison, M.R.,Munster, V.J.,Mascola, J.R.,Graham, B.S. Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape. J. Virol., 92:-, 2018 Cited by PubMed: 29514901DOI: 10.1128/JVI.02002-17 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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