3J1C
 
 | | Cryo-EM structure of 9-fold symmetric rATcpn-alpha in apo state | | Descriptor: | Chaperonin alpha subunit | | Authors: | Zhang, K, Wang, L, Liu, Y.X, Wang, X, Gao, B, Hu, Z.J, Ji, G, Chan, K.Y, Schulten, K, Dong, Z.Y, Sun, F. | | Deposit date: | 2012-02-06 | | Release date: | 2013-08-07 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (9.1 Å) | | Cite: | Flexible interwoven termini determine the thermal stability of thermosomes.
Protein Cell, 4, 2013
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5EJO
 | | Crystal structure of the winged helix domain in Chromatin assembly factor 1 subunit p90 | | Descriptor: | Chromatin assembly factor 1 subunit p90 | | Authors: | Zhang, K, Gao, Y, Li, J, Burgess, R, Han, J, Liang, H, Zhang, Z, Liu, Y. | | Deposit date: | 2015-11-02 | | Release date: | 2016-03-16 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks
Nucleic Acids Res., 44, 2016
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3J1F
 | | Cryo-EM structure of 9-fold symmetric rATcpn-beta in ATP-binding state | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin beta subunit, MAGNESIUM ION | | Authors: | Zhang, K, Wang, L, Liu, Y.X, Wang, X, Gao, B, Hu, Z.J, Ji, G, Chan, K.Y, Schulten, K, Dong, Z.Y, Sun, F. | | Deposit date: | 2012-02-06 | | Release date: | 2013-08-07 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (6.2 Å) | | Cite: | Flexible interwoven termini determine the thermal stability of thermosomes.
Protein Cell, 4, 2013
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8CXO
 | | Cryo-EM structure of the unliganded mSMO-PGS2 in a lipidic environment | | Descriptor: | CHOLESTEROL, Smoothened homolog, GlgA glycogen synthase chimera | | Authors: | Zhang, K, Wu, H, Hoppe, N, Manglik, A, Cheng, Y. | | Deposit date: | 2022-05-22 | | Release date: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Fusion protein strategies for cryo-EM study of G protein-coupled receptors.
Nat Commun, 13, 2022
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6VQV
 | | Type I-F CRISPR-Csy complex with its inhibitor AcrF9 | | Descriptor: | AcrF9, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | | Authors: | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | | Deposit date: | 2020-02-06 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.57 Å) | | Cite: | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6VQX
 | | Type I-F CRISPR-Csy complex with its inhibitor AcrF6 | | Descriptor: | AcrF6, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | | Authors: | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | | Deposit date: | 2020-02-06 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6VQW
 | | Type I-F CRISPR-Csy complex with its inhibitor AcrF8 | | Descriptor: | AcrF8, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | | Authors: | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | | Deposit date: | 2020-02-06 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7TB3
 | | cryo-EM structure of MBP-KIX-apoferritin | | Descriptor: | Isoform 2 of CREB-binding protein,Ferritin heavy chain, N-terminally processed | | Authors: | Zhang, K, Horikoshi, N, Li, S, Powers, A, Hameedi, M, Pintilie, G, Chae, H, Khan, Y, Suomivuori, C, Dror, R, Sakamoto, K, Chiu, W, Wakatsuki, S. | | Deposit date: | 2021-12-21 | | Release date: | 2022-03-16 | | Method: | ELECTRON MICROSCOPY (2.57 Å) | | Cite: | Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia.
Acs Cent.Sci., 8, 2022
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7TBH
 | | cryo-EM structure of MBP-KIX-apoferritin complex with peptide 7 | | Descriptor: | Isoform 2 of CREB-binding protein,Ferritin heavy chain, N-terminally processed, LEU-SER-ARG-ARG-PRO-SEP-TYR-ARG-LYS-ILE-LEU-ASN-ASP-LEU-SER-SER-ASP-ALA-PRO | | Authors: | Zhang, K, Horikoshi, N, Li, S, Powers, A, Hameedi, M, Pintilie, G, Chae, H, Khan, Y, Suomivuori, C, Dror, R, Sakamoto, K, Chiu, W, Wakatsuki, S. | | Deposit date: | 2021-12-22 | | Release date: | 2022-03-16 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia.
Acs Cent.Sci., 8, 2022
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5FHP
 | | SeMet regulator of nicotine degradation | | Descriptor: | GLYCEROL, MALONIC ACID, NicR | | Authors: | Zhang, K, Tang, H, Wu, G, Wang, W, Hu, H, Xu, P. | | Deposit date: | 2015-12-22 | | Release date: | 2016-12-21 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Co-crystal Structure of NicR2_Hsp
To Be Published
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5FGL
 | | Co-crystal Structure of NicR2_Hsp | | Descriptor: | 4-oxidanylidene-4-(6-oxidanylidene-1~{H}-pyridin-3-yl)butanoic acid, NicR | | Authors: | Zhang, K, Tang, H, Wu, G, Wang, W, Hu, H, Xu, P. | | Deposit date: | 2015-12-21 | | Release date: | 2016-12-21 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Co-crystal Structure of NicR2_Hsp
To Be Published
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7XN5
 | | Cryo-EM structure of CopC-CaM-caspase-3 with ADPR | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Arginine ADP-riboxanase CopC, Calmodulin-1, ... | | Authors: | Zhang, K, Peng, T, Tao, X.Y, Tian, M, Li, Y.X, Wang, Z, Ma, S.F, Hu, S.F, Pan, X, Xue, J, Luo, J.W, Wu, Q.L, Fu, Y, Li, S. | | Deposit date: | 2022-04-28 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-28 | | Method: | ELECTRON MICROSCOPY (3.18 Å) | | Cite: | Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin.
Mol.Cell, 82, 2022
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7DOP
 | | Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1 | | Descriptor: | Nonstructural Protein 1, ZINC ION | | Authors: | Zhang, K, Law, Y.S, Law, M.C.Y, Tan, Y.B, Wirawan, M, Luo, D.H. | | Deposit date: | 2020-12-15 | | Release date: | 2021-03-24 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.38 Å) | | Cite: | Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1.
Cell Host Microbe, 29, 2021
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7X01
 | | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with inhibitor FHA | | Descriptor: | (1R,2S,3S,4R,5R)-3-(6-aminopurin-9-yl)-4-fluoranyl-5-(2-hydroxyethyl)cyclopentane-1,2-diol, ZINC ION, mRNA-capping enzyme nsP1 | | Authors: | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | | Deposit date: | 2022-02-20 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (2.62 Å) | | Cite: | Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1.
Cell Rep, 40, 2022
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7XN6
 | | Cryo-EM structure of CopC-CaM-caspase-3 with ADPR-deacylization | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Arginine ADP-riboxanase CopC, Calmodulin-1, ... | | Authors: | Zhang, K, Peng, T, Tao, X.Y, Tian, M, Li, Y.X, Wang, Z, Ma, S.F, Hu, S.F, Pan, X, Xue, J, Luo, J.W, Wu, Q.L, Fu, Y, Li, S. | | Deposit date: | 2022-04-28 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-28 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin.
Mol.Cell, 82, 2022
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7XN4
 | | Cryo-EM structure of CopC-CaM-caspase-3 with NAD+ | | Descriptor: | Arginine ADP-riboxanase CopC, Calmodulin-1, Caspase-3, ... | | Authors: | Zhang, K, Peng, T, Tao, X.Y, Tian, M, Li, Y.X, Wang, Z, Ma, S.F, Hu, S.F, Pan, X, Xue, J, Luo, J.W, Wu, Q.L, Fu, Y, Li, S. | | Deposit date: | 2022-04-28 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-28 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin.
Mol.Cell, 82, 2022
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7FGH
 | | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GMP | | Descriptor: | N7-METHYL-GUANOSINE-5'-MONOPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... | | Authors: | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | | Deposit date: | 2021-07-27 | | Release date: | 2022-07-27 | | Last modified: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (2.18 Å) | | Cite: | Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1.
Cell Rep, 40, 2022
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7FGG
 | | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GTP | | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | | Deposit date: | 2021-07-27 | | Release date: | 2022-07-27 | | Last modified: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (2.19 Å) | | Cite: | Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1.
Cell Rep, 40, 2022
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7FGI
 | | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7Gppp-AU | | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ... | | Authors: | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | | Deposit date: | 2021-07-27 | | Release date: | 2022-07-27 | | Last modified: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (2.51 Å) | | Cite: | Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1.
Cell Rep, 40, 2022
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7K3V
 | | Apoferritin structure at 1.34 angstrom resolution determined from a 300 kV Titan Krios G3i electron microscope with K3 detector | | Descriptor: | Ferritin heavy chain, SODIUM ION, ZINC ION | | Authors: | Zhang, K, Pintilie, G, Li, S, Schmid, M, Chiu, W. | | Deposit date: | 2020-09-14 | | Release date: | 2020-11-18 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (1.34 Å) | | Cite: | Resolving individual atoms of protein complex by cryo-electron microscopy.
Cell Res., 30, 2020
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7K3W
 | | Apoferritin structure at 1.36 angstrom resolution determined from a 300 kV Titan Krios G3i electron microscope with Falcon4 detector | | Descriptor: | Ferritin heavy chain, SODIUM ION, ZINC ION | | Authors: | Zhang, K, Pintilie, G, Li, S, Schmid, M, Chiu, W. | | Deposit date: | 2020-09-14 | | Release date: | 2020-11-18 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (1.36 Å) | | Cite: | Resolving individual atoms of protein complex by cryo-electron microscopy.
Cell Res., 30, 2020
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7KIP
 | | A 3.4 Angstrom cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Zhang, K, Li, S, Pintilie, G, Chmielewski, D, Schmid, M, Simmons, G, Jin, J, Chiu, W. | | Deposit date: | 2020-10-24 | | Release date: | 2020-11-11 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | A 3.4- angstrom cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles.
Biorxiv, 2020
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7L2N
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7L2O
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7L2L
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