7TBH

cryo-EM structure of MBP-KIX-apoferritin complex with peptide 7

Summary for 7TBH

Entry DOI	10.2210/pdb7tbh/pdb
EMDB information	25799
Descriptor	Isoform 2 of CREB-binding protein,Ferritin heavy chain, N-terminally processed, LEU-SER-ARG-ARG-PRO-SEP-TYR-ARG-LYS-ILE-LEU-ASN-ASP-LEU-SER-SER-ASP-ALA-PRO (2 entities in total)
Functional Keywords	protein engineering, simulation, peptide therapeutics, acute myeloid leukemia, structural protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	48
Total formula weight	784341.48
Authors	Zhang, K.,Horikoshi, N.,Li, S.,Powers, A.,Hameedi, M.,Pintilie, G.,Chae, H.,Khan, Y.,Suomivuori, C.,Dror, R.,Sakamoto, K.,Chiu, W.,Wakatsuki, S. (deposition date: 2021-12-22, release date: 2022-03-16)
Primary citation	Zhang, K.,Horikoshi, N.,Li, S.,Powers, A.S.,Hameedi, M.A.,Pintilie, G.D.,Chae, H.D.,Khan, Y.A.,Suomivuori, C.M.,Dror, R.O.,Sakamoto, K.M.,Chiu, W.,Wakatsuki, S. Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia. Acs Cent.Sci., 8:214-222, 2022 Cited by PubMed: 35233453 DOI: 10.1021/acscentsci.1c01090 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.3 Å)

Structure validation