8CXO
Cryo-EM structure of the unliganded mSMO-PGS2 in a lipidic environment
Summary for 8CXO
Entry DOI | 10.2210/pdb8cxo/pdb |
EMDB information | 27062 27063 |
Descriptor | Smoothened homolog, GlgA glycogen synthase chimera, CHOLESTEROL (2 entities in total) |
Functional Keywords | g-protein coupled receptor, smoothened, unliganded state, lipid system, membrane protein |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 1 |
Total formula weight | 81254.83 |
Authors | Zhang, K.,Wu, H.,Hoppe, N.,Manglik, A.,Cheng, Y. (deposition date: 2022-05-22, release date: 2022-08-03, Last modification date: 2024-05-01) |
Primary citation | Zhang, K.,Wu, H.,Hoppe, N.,Manglik, A.,Cheng, Y. Fusion protein strategies for cryo-EM study of G protein-coupled receptors. Nat Commun, 13:4366-4366, 2022 Cited by PubMed: 35902590DOI: 10.1038/s41467-022-32125-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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