8CXO

Cryo-EM structure of the unliganded mSMO-PGS2 in a lipidic environment

Summary for 8CXO

• Entry DOI: 10.2210/pdb8cxo/pdb
• EMDB information: 27062 27063
• Descriptor: Smoothened homolog, GlgA glycogen synthase chimera, CHOLESTEROL (2 entities in total)
• Functional Keywords: g-protein coupled receptor, smoothened, unliganded state, lipid system, membrane protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 1
• Total formula weight: 81254.83

Authors

Zhang, K.,Wu, H.,Hoppe, N.,Manglik, A.,Cheng, Y. (deposition date: 2022-05-22, release date: 2022-08-03)

• Primary citation: Zhang, K.,Wu, H.,Hoppe, N.,Manglik, A.,Cheng, Y.; Fusion protein strategies for cryo-EM study of G protein-coupled receptors.; Nat Commun, 13:4366-, 2022; DOI: 10.1038/s41467-022-32125-2

Experimental method

ELECTRON MICROSCOPY (3.7 Å)