8CXO
Cryo-EM structure of the unliganded mSMO-PGS2 in a lipidic environment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Smoothened homolog, GlgA glycogen synthase chimera | polymer | 719 | 80868.2 | 1 | UniProt (P56726) UniProt (Q9V2J8) Pfam (PF01392) Pfam (PF01534) Pfam (PF13692) | Mus musculus (house mouse) | SMO,Glycogen synthase |
| 2 | B (A) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) |
Sequence modifications
A: 64 - 441 (UniProt: P56726)
A: 1001 - 1196 (UniProt: Q9V2J8)
A: 450 - 566 (UniProt: P56726)
| PDB | External Database | Details |
|---|---|---|
| Trp 47 | - | expression tag |
| Ser 48 | - | expression tag |
| His 49 | - | expression tag |
| Pro 50 | - | expression tag |
| Gln 51 | - | expression tag |
| Phe 52 | - | expression tag |
| Glu 53 | - | expression tag |
| Lys 54 | - | expression tag |
| Glu 55 | - | expression tag |
| Asn 56 | - | expression tag |
| Leu 57 | - | expression tag |
| Tyr 58 | - | expression tag |
| Phe 59 | - | expression tag |
| Gln 60 | - | expression tag |
| Ser 61 | - | expression tag |
| Pro 62 | - | expression tag |
| Arg 63 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp 1197 | - | linker |
| Gln 1198 | - | linker |
| Ala 1199 | - | linker |
| Arg 1200 | - | linker |
| Met 1201 | - | linker |
| Asp 1202 | - | linker |
| Ile 1203 | - | linker |
| Arg 1204 | - | linker |
| Leu 1205 | - | linker |
| Ala 1206 | - | linker |
| Lys 1207 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 80868.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 386.7 | |
| All* | Total formula weight | 81254.8 |
