7TB3

cryo-EM structure of MBP-KIX-apoferritin

Summary for 7TB3

• Entry DOI: 10.2210/pdb7tb3/pdb
• EMDB information: 25791
• Descriptor: Isoform 2 of CREB-binding protein,Ferritin heavy chain, N-terminally processed (1 entity in total)
• Functional Keywords: protein engineering, simulation, peptide therapeutics, acute myeloid leukemia, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 24
• Total formula weight: 729802.51

Authors

Zhang, K.,Horikoshi, N.,Li, S.,Powers, A.,Hameedi, M.,Pintilie, G.,Chae, H.,Khan, Y.,Suomivuori, C.,Dror, R.,Sakamoto, K.,Chiu, W.,Wakatsuki, S. (deposition date: 2021-12-21, release date: 2022-03-16)

• Primary citation: Zhang, K.,Horikoshi, N.,Li, S.,Powers, A.S.,Hameedi, M.A.,Pintilie, G.D.,Chae, H.D.,Khan, Y.A.,Suomivuori, C.M.,Dror, R.O.,Sakamoto, K.M.,Chiu, W.,Wakatsuki, S.; Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia.; Acs Cent.Sci., 8:214-222, 2022; PubMed: 35233453; DOI: 10.1021/acscentsci.1c01090

Experimental method

ELECTRON MICROSCOPY (2.57 Å)