7XN4

Cryo-EM structure of CopC-CaM-caspase-3 with NAD+

Summary for 7XN4

• Entry DOI: 10.2210/pdb7xn4/pdb
• EMDB information: 33310
• Descriptor: Caspase-3, Arginine ADP-riboxanase CopC, Calmodulin-1, ... (4 entities in total)
• Functional Keywords: type iii secretion system, chromobacterium violaceum, caspase-3, new ptm, programmed cell deatha, dp-ribosylation, adpr-deacylization, toxin
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 133805.36

Authors

Zhang, K.,Peng, T.,Tao, X.Y.,Tian, M.,Li, Y.X.,Wang, Z.,Ma, S.F.,Hu, S.F.,Pan, X.,Xue, J.,Luo, J.W.,Wu, Q.L.,Fu, Y.,Li, S. (deposition date: 2022-04-28, release date: 2022-12-14, Last modification date: 2022-12-28)

• Primary citation: Zhang, K.,Peng, T.,Tao, X.,Tian, M.,Li, Y.,Wang, Z.,Ma, S.,Hu, S.,Pan, X.,Xue, J.,Luo, J.,Wu, Q.,Fu, Y.,Li, S.; Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin.; Mol.Cell, 82:4712-4726.e7, 2022; PubMed: 36423631; DOI: 10.1016/j.molcel.2022.10.032

Experimental method

ELECTRON MICROSCOPY (3.35 Å)