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5KGN
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BU of 5kgn by Molmil
1.95A resolution structure of independent phosphoglycerate mutase from C. elegans in complex with a macrocyclic peptide inhibitor (2d)
Descriptor: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, CHLORIDE ION, GLYCEROL, ...
Authors:Lovell, S, Mehzabeen, N, Battaile, K.P, Yu, H, Dranchak, P, MacArthur, R, Li, Z, Carlow, T, Suga, H, Inglese, J.
Deposit date:2016-06-13
Release date:2017-04-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases.
Nat Commun, 8, 2017
5KGM
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BU of 5kgm by Molmil
2.95A resolution structure of Apo independent phosphoglycerate mutase from C. elegans (monoclinic form)
Descriptor: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, CHLORIDE ION, MANGANESE (II) ION, ...
Authors:Lovell, S, Mehzabeen, N, Battaile, K.P, Yu, H, Dranchak, P, MacArthur, R, Li, Z, Carlow, T, Suga, H, Inglese, J.
Deposit date:2016-06-13
Release date:2017-04-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases.
Nat Commun, 8, 2017
5KGL
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BU of 5kgl by Molmil
2.45A resolution structure of Apo independent phosphoglycerate mutase from C. elegans (orthorhombic form)
Descriptor: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, CHLORIDE ION, MANGANESE (II) ION, ...
Authors:Lovell, S, Mehzabeen, N, Battaile, K.P, Yu, H, Dranchak, P, MacArthur, R, Li, Z, Carlow, T, Suga, H, Inglese, J.
Deposit date:2016-06-13
Release date:2017-04-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases.
Nat Commun, 8, 2017
2CCD
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BU of 2ccd by Molmil
Crystal structure of the catalase-peroxidase (KatG) and S315T mutant from Mycobacterium tuberculosis
Descriptor: PEROXIDASE/CATALASE T, PROTOPORPHYRIN IX CONTAINING FE
Authors:Yu, H, Sacchettini, J.C.
Deposit date:2006-01-16
Release date:2006-01-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Hydrogen Peroxide-Mediated Isoniazid Activation Catalyzed by Mycobacterium Tuberculosis Catalase- Peroxidase (Katg) and its S315T Mutant.
Biochemistry, 45, 2006
2CCA
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BU of 2cca by Molmil
Crystal structure of the catalase-peroxidase (KatG) and S315T mutant from Mycobacterium tuberculosis
Descriptor: PEROXIDASE/CATALASE T, PROTOPORPHYRIN IX CONTAINING FE
Authors:Yu, H, Sacchettini, J.C.
Deposit date:2006-01-16
Release date:2006-01-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrogen Peroxide-Mediated Isoniazid Activation Catalyzed by Mycobacterium Tuberculosis Catalase-Peroxidase (Katg) and its S315T Mutant.
Biochemistry, 45, 2006
6WIV
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BU of 6wiv by Molmil
Structure of human GABA(B) receptor in an inactive state
Descriptor: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-{[(9Z)-octadec-9-enoyl]oxy}propyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Park, J, Fu, Z, Frangaj, A, Liu, J, Mosyak, L, Shen, T, Slavkovich, V.N, Ray, K.M, Taura, J, Cao, B, Geng, Y, Zuo, H, Kou, Y, Grassucci, R, Chen, S, Liu, Z, Lin, X, Williams, J.P, Rice, W.J, Eng, E.T, Huang, R.K, Soni, R.K, Kloss, B, Yu, Z, Javitch, J.A, Hendrickson, W.A, Slesinger, P.A, Quick, M, Graziano, J, Yu, H, Fiehn, O, Clarke, O.B, Frank, J, Fan, Q.R.
Deposit date:2020-04-10
Release date:2020-07-01
Last modified:2020-08-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of human GABABreceptor in an inactive state.
Nature, 584, 2020
1PRM
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BU of 1prm by Molmil
TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS
Descriptor: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND PLR1 (AFAPPLPRR)
Authors:Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L.
Deposit date:1994-10-10
Release date:1995-02-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.
Science, 266, 1994
1PRL
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BU of 1prl by Molmil
TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS
Descriptor: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND PLR1 (AFAPPLPRR)
Authors:Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L.
Deposit date:1994-10-10
Release date:1995-02-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.
Science, 266, 1994
1RLQ
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BU of 1rlq by Molmil
TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS
Descriptor: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND RLP2 (RALPPLPRY)
Authors:Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L.
Deposit date:1994-10-10
Release date:1995-02-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.
Science, 266, 1994
1RLP
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BU of 1rlp by Molmil
TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS
Descriptor: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND RLP2 (RALPPLPRY)
Authors:Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L.
Deposit date:1994-10-10
Release date:1995-02-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.
Science, 266, 1994
1S2H
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BU of 1s2h by Molmil
The Mad2 spindle checkpoint protein possesses two distinct natively folded states
Descriptor: Mitotic spindle assembly checkpoint protein MAD2A
Authors:Luo, X, Tang, Z, Xia, G, Wassmann, K, Matsumoto, T, Rizo, J, Yu, H.
Deposit date:2004-01-08
Release date:2004-03-30
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:The Mad2 spindle checkpoint protein has two distinct natively folded states.
Nat.Struct.Mol.Biol., 11, 2004
2VFX
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BU of 2vfx by Molmil
Structure of the Symmetric Mad2 Dimer
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ...
Authors:Yang, M, Li, B, Liu, C.-J, Tomchick, D.R, Machius, M, Rizo, J, Yu, H, Luo, X.
Deposit date:2007-11-05
Release date:2008-03-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer.
Plos Biol., 6, 2008
1PKS
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BU of 1pks by Molmil
STRUCTURE OF THE PI3K SH3 DOMAIN AND ANALYSIS OF THE SH3 FAMILY
Descriptor: PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT SH3 DOMAIN
Authors:Koyama, S, Yu, H, Dalgarno, D.C, Shin, T.B, Zydowsky, L.D, Schreiber, S.L.
Deposit date:1994-03-07
Release date:1994-05-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structure of the PI3K SH3 domain and analysis of the SH3 family.
Cell(Cambridge,Mass.), 72, 1993
1PKT
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BU of 1pkt by Molmil
STRUCTURE OF THE PI3K SH3 DOMAIN AND ANALYSIS OF THE SH3 FAMILY
Descriptor: PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT SH3 DOMAIN
Authors:Koyama, S, Yu, H, Dalgarno, D.C, Shin, T.B, Zydowsky, L.D, Schreiber, S.L.
Deposit date:1994-03-07
Release date:1994-05-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structure of the PI3K SH3 domain and analysis of the SH3 family.
Cell(Cambridge,Mass.), 72, 1993
1DUJ
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BU of 1duj by Molmil
SOLUTION STRUCTURE OF THE SPINDLE ASSEMBLY CHECKPOINT PROTEIN HUMAN MAD2
Descriptor: SPINDLE ASSEMBLY CHECKPOINT PROTEIN
Authors:Luo, X, Fang, G, Coldiron, M, Lin, Y, Yu, H.
Deposit date:2000-01-17
Release date:2000-03-08
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20.
Nat.Struct.Biol., 7, 2000
6E15
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BU of 6e15 by Molmil
Handover mechanism of the growing pilus by the bacterial outer membrane usher FimD
Descriptor: Chaperone protein FimC, Fimbrial biogenesis outer membrane usher protein, Protein FimF, ...
Authors:Du, M, Yuan, Z, Yu, H, Henderson, N, Sarowar, S, Zhao, G, Werneburg, G.T, Thanassi, D.G, Li, H.
Deposit date:2018-07-09
Release date:2018-10-17
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD.
Nature, 562, 2018
6E14
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BU of 6e14 by Molmil
Handover mechanism of the growing pilus by the bacterial outer membrane usher FimD
Descriptor: Chaperone protein FimC, Fimbrial biogenesis outer membrane usher protein, Protein FimF, ...
Authors:Du, M, Yuan, Z, Yu, H, Henderson, N, Sarowar, S, Zhao, G, Werneburg, G.T, Thanassi, D.G, Li, H.
Deposit date:2018-07-09
Release date:2018-10-17
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD.
Nature, 562, 2018
6WG3
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BU of 6wg3 by Molmil
Cryo-EM structure of human Cohesin-NIPBL-DNA complex
Descriptor: Cohesin subunit SA-1, DNA (51-MER), Double-strand-break repair protein rad21 homolog, ...
Authors:Shi, Z.B, Gao, H, Bai, X.C, Yu, H.
Deposit date:2020-04-04
Release date:2020-05-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Science, 368, 2020
6WGE
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BU of 6wge by Molmil
Cryo-EM structure of human Cohesin-NIPBL-DNA complex without STAG1
Descriptor: DNA (43-MER), Double-strand-break repair protein rad21 homolog, MAGNESIUM ION, ...
Authors:Shi, Z.B, Gao, H, Bai, X.C, Yu, H.
Deposit date:2020-04-05
Release date:2020-05-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Science, 368, 2020
6WG4
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BU of 6wg4 by Molmil
Crystal structure of human SMC1-SMC3 hinge domain heterodimer in south-open conformation
Descriptor: Structural maintenance of chromosomes protein, Structural maintenance of chromosomes protein 3
Authors:Shi, Z.B, Yu, H.
Deposit date:2020-04-04
Release date:2020-05-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Science, 368, 2020
6WSL
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BU of 6wsl by Molmil
Cryo-EM structure of VASH1-SVBP bound to microtubules
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Small vasohibin-binding protein, ...
Authors:Li, F, Li, Y, Yu, H.
Deposit date:2020-05-01
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of VASH1-SVBP bound to microtubules.
Elife, 9, 2020
6WG6
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BU of 6wg6 by Molmil
Crystal structure of human SMC1-SMC3 hinge domain heterodimer in north-open conformation
Descriptor: Structural maintenance of chromosomes protein, Structural maintenance of chromosomes protein 3, poly(dT)
Authors:Shi, Z.B, Yu, H.
Deposit date:2020-04-04
Release date:2020-05-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Science, 368, 2020
3Q6S
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BU of 3q6s by Molmil
The crystal structure of the heterochromatin protein 1 beta chromoshadow domain complexed with a peptide from Shugoshin 1
Descriptor: Chromobox protein homolog 1, Shugoshin-like 1
Authors:Brautigam, C.A, Chaudhary, J, Yu, H.
Deposit date:2011-01-03
Release date:2011-12-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells.
Mol Biol Cell, 22, 2011
3SHU
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BU of 3shu by Molmil
Crystal structure of ZO-1 PDZ3
Descriptor: Tight junction protein ZO-1
Authors:Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M.
Deposit date:2011-06-17
Release date:2011-09-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
4R8Q
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BU of 4r8q by Molmil
Structure and substrate recruitment of the human spindle checkpoint kinase bub1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitotic checkpoint serine/threonine-protein kinase BUB1
Authors:Tomchick, D.R, Yu, H.
Deposit date:2014-09-02
Release date:2014-11-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structure and substrate recruitment of the human spindle checkpoint kinase Bub1.
Mol.Cell, 32, 2008

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