1PRM

TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS

Summary for 1PRM
DescriptorC-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND PLR1 (AFAPPLPRR) (2 entities in total)
Functional Keywordscomplex (signal transduction-peptide), complex (signal transduction-peptide) complex, complex (signal transduction/peptide)
Biological sourceGallus gallus (chicken)
Cellular locationCell membrane (By similarity): P00523
Total number of polymer chains2
Total formula weight8029.88
Authors
Feng, S.,Chen, J.K.,Yu, H.,Simon, J.A.,Schreiber, S.L. (deposition date: 1994-10-10, release date: 1995-02-07, Last modification date: 2011-07-13)
Primary citationChen, J.K.,Feng, S.,Schreiber, S.L.,Simon, J.A.,Yu, H.
Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.
Science, 266:1241-1247, 1994
PubMed: 7526465
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation
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PDB entries from 2021-06-16