5TJ7
 
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5TJQ
 | | Structure of WWP2 2,3-linker-HECT | | 分子名称: | NEDD4-like E3 ubiquitin-protein ligase WWP2,NEDD4-like E3 ubiquitin-protein ligase WWP2 | | 著者 | Chen, Z, Gabelli, S.B. | | 登録日 | 2016-10-04 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | A Tunable Brake for HECT Ubiquitin Ligases.
Mol. Cell, 66, 2017
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5U1R
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5U17
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5U2V
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5U16
 | | Structure of human MR1-2-OH-1-NA in complex with human MAIT A-F7 TCR | | 分子名称: | 2-hydroxynaphthalene-1-carbaldehyde, Beta-2-microglobulin, CHLORIDE ION, ... | | 著者 | Keller, A.N, Birkinshaw, R.W, Rossjohn, J. | | 登録日 | 2016-11-27 | | 公開日 | 2017-02-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.
Nat. Immunol., 18, 2017
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5U6Q
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6JDE
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6IWV
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6JGY
 | | Crystal structure of LASV-GP2 in a post fusion conformation | | 分子名称: | Pre-glycoprotein polyprotein GP complex | | 著者 | Zhu, Y, Zhang, X, Chen, B, Ye, S, Zhang, R. | | 登録日 | 2019-02-15 | | 公開日 | 2019-09-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.389 Å) | | 主引用文献 | Crystal Structure of Refolding Fusion Core of Lassa Virus GP2 and Design of Lassa Virus Fusion Inhibitors.
Front Microbiol, 10, 2019
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6JRK
 | | The structure of co-crystals of 8r-B-EGFR WT complex | | 分子名称: | 6-(2-chloranyl-3-fluoranyl-phenyl)-5-methyl-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[(3S)-1-propanoylpiperidin-3-yl]pyrido[2,3-d]pyrimidin-7-one, Epidermal growth factor receptor | | 著者 | Zhu, S.J, Yun, C.H. | | 登録日 | 2019-04-04 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.796 Å) | | 主引用文献 | Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFRL858R/T790M/C797S).
J.Med.Chem., 62, 2019
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6JRJ
 | | The structure of co-crystals of 8r-B-EGFR T790M/C797S complex | | 分子名称: | 6-(2-chloranyl-3-fluoranyl-phenyl)-5-methyl-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[(3S)-1-propanoylpiperidin-3-yl]pyrido[2,3-d]pyrimidin-7-one, Epidermal growth factor receptor | | 著者 | Zhu, S.J, Yun, C.H. | | 登録日 | 2019-04-04 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.943 Å) | | 主引用文献 | Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFRL858R/T790M/C797S).
J.Med.Chem., 62, 2019
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5WI4
 | | CRYSTAL STRUCTURE OF DYNLT1/TCTEX-1 IN COMPLEX WITH ARHGEF2 | | 分子名称: | Dynein light chain Tctex-type 1,Rho guanine nucleotide exchange factor 2, SULFATE ION | | 著者 | Balan, M, Ishiyama, N, Marshall, C.B, Ikura, M. | | 登録日 | 2017-07-18 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.
Sci Signal, 10, 2017
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2O1C
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2O5W
 | | Structure of the E. coli dihydroneopterin triphosphate pyrophosphohydrolase in complex with Sm+3 and pyrophosphate | | 分子名称: | PYROPHOSPHATE, SAMARIUM (III) ION, SODIUM ION, ... | | 著者 | Gabelli, S.B, Bianchet, M.A, Amzel, L.M. | | 登録日 | 2006-12-06 | | 公開日 | 2007-08-28 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure and function of the E. coli dihydroneopterin triphosphate pyrophosphatase: a Nudix enzyme involved in folate biosynthesis.
Structure, 15, 2007
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2O6X
 | | Crystal Structure of ProCathepsin L1 from Fasciola hepatica | | 分子名称: | Secreted cathepsin L 1 | | 著者 | Brinen, L.S, Dalton, J.P, Geiger, S, Marion, R, Stack, C.M. | | 登録日 | 2006-12-08 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica.
J.Biol.Chem., 283, 2008
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3DNU
 | | structure of MDT protein | | 分子名称: | CHLORIDE ION, PHOSPHATE ION, Protein hipA | | 著者 | schumacher, M.A. | | 登録日 | 2008-07-02 | | 公開日 | 2009-01-27 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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3DNF
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3DNT
 | | structures of MDT proteins | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein hipA, ... | | 著者 | Schumacher, M.A. | | 登録日 | 2008-07-02 | | 公開日 | 2009-01-27 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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3DNV
 | | MDT Protein | | 分子名称: | DNA (5'-D(*DAP*DCP*DTP*DAP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DTP*DAP*DG)-3'), HTH-type transcriptional regulator hipB, Protein hipA, ... | | 著者 | schumacher, M.A. | | 登録日 | 2008-07-02 | | 公開日 | 2009-01-27 | | 最終更新日 | 2023-04-05 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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3EZ7
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3EZ9
 | | Partition Protein | | 分子名称: | MAGNESIUM ION, ParA | | 著者 | Schumacher, M.A. | | 登録日 | 2008-10-22 | | 公開日 | 2009-06-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for ADP-mediated transcriptional regulation by P1 and P7 ParA.
Embo J., 28, 2009
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3EZF
 | | Partition Protein | | 分子名称: | ParA, SULFATE ION | | 著者 | Schumacher, M.A. | | 登録日 | 2008-10-22 | | 公開日 | 2009-06-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for ADP-mediated transcriptional regulation by P1 and P7 ParA.
Embo J., 28, 2009
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3EZ6
 | | Structure of parA-ADP complex:tetragonal form | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Plasmid partition protein A | | 著者 | Schumacher, M.A. | | 登録日 | 2008-10-22 | | 公開日 | 2009-06-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Structural basis for ADP-mediated transcriptional regulation by P1 and P7 ParA.
Embo J., 28, 2009
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3FBR
 | | structure of HipA-amppnp-peptide | | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase toxin HipA, peptide of EF-Tu | | 著者 | Schumacher, M.A. | | 登録日 | 2008-11-19 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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