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PDB: 3 results

2O6X
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BU of 2o6x by Molmil
Crystal Structure of ProCathepsin L1 from Fasciola hepatica
Descriptor: Secreted cathepsin L 1
Authors:Brinen, L.S, Dalton, J.P, Geiger, S, Marion, R, Stack, C.M.
Deposit date:2006-12-08
Release date:2007-12-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica.
J.Biol.Chem., 283, 2008
2P86
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The high resolution crystal structure of rhodesain, the major cathepsin L protease from T. brucei rhodesiense, bound to inhibitor K11002
Descriptor: 1,2-ETHANEDIOL, 3-[[N-[MORPHOLIN-N-YL]-CARBONYL]-PHENYLALANINYL-AMINO]-5- PHENYL-PENTANE-1-SULFONYLBENZENE, Cysteine protease
Authors:Brinen, L.S, Marion, R.
Deposit date:2007-03-21
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:THE high resolution structure of rhodesain, the major cathepsin L protease from trypanosoma brucei rhodesiense, illustrates the basis for differences in inhibition profiles from other papain family cysteine proteases
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2P7U
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The crystal structure of rhodesain, the major cysteine protease of T. brucei rhodesiense, bound to inhibitor K777
Descriptor: Cysteine protease, NALPHA-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-N-{(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}-L-PHENYLALANINAMIDE
Authors:Brinen, L.S, Marion, R.
Deposit date:2007-03-20
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Vinyl sulfones as antiparasitic agents and a structural basis for drug design.
J.Biol.Chem., 284, 2009

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