2O6X

Crystal Structure of ProCathepsin L1 from Fasciola hepatica

Summary for 2O6X

Entry DOI	10.2210/pdb2o6x/pdb
Related	1CJL
Descriptor	Secreted cathepsin L 1 (2 entities in total)
Functional Keywords	hydrolase; thiol protease; cysteine protease; zymogen, hydrolase
Biological source	Fasciola hepatica (liver fluke)
Total number of polymer chains	1
Total formula weight	35109.12
Authors	Brinen, L.S.,Dalton, J.P.,Geiger, S.,Marion, R.,Stack, C.M. (deposition date: 2006-12-08, release date: 2007-12-18, Last modification date: 2023-08-30)
Primary citation	Stack, C.M.,Caffrey, C.R.,Donnelly, S.M.,Seshaadri, A.,Lowther, J.,Tort, J.F.,Collins, P.R.,Robinson, M.W.,Xu, W.,McKerrow, J.H.,Craik, C.S.,Geiger, S.R.,Marion, R.,Brinen, L.S.,Dalton, J.P. Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica. J.Biol.Chem., 283:9896-9908, 2008 Cited by PubMed: 18160404 DOI: 10.1074/jbc.M708521200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation