5U2V

Structure of human MR1-HMB in complex with human MAIT A-F7 TCR

Summary for 5U2V

• Entry DOI: 10.2210/pdb5u2v/pdb
• Related: 5U16 5U17 5U1R 5U6Q
• Descriptor: Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, MAIT T-cell receptor alpha chain, ... (8 entities in total)
• Functional Keywords: t-cell receptor complex, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 187916.54

Authors

Keller, A.N.,Rossjohn, J. (deposition date: 2016-12-01, release date: 2017-02-08, Last modification date: 2023-10-04)

• Primary citation: Keller, A.N.,Eckle, S.B.,Xu, W.,Liu, L.,Hughes, V.A.,Mak, J.Y.,Meehan, B.S.,Pediongco, T.,Birkinshaw, R.W.,Chen, Z.,Wang, H.,D'Souza, C.,Kjer-Nielsen, L.,Gherardin, N.A.,Godfrey, D.I.,Kostenko, L.,Corbett, A.J.,Purcell, A.W.,Fairlie, D.P.,McCluskey, J.,Rossjohn, J.; Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.; Nat. Immunol., 18:402-411, 2017; PubMed: 28166217; DOI: 10.1038/ni.3679

Experimental method

X-RAY DIFFRACTION (2.2 Å)