5WI4

CRYSTAL STRUCTURE OF DYNLT1/TCTEX-1 IN COMPLEX WITH ARHGEF2

Summary for 5WI4

Entry DOI	10.2210/pdb5wi4/pdb
Descriptor	Dynein light chain Tctex-type 1,Rho guanine nucleotide exchange factor 2, SULFATE ION (3 entities in total)
Functional Keywords	dynein light chain, rho gef, motor protein, cargo transport
Biological source	Mus musculus (Mouse) More
Cellular location	Cytoplasm, cytoskeleton : Q60875
Total number of polymer chains	3
Total formula weight	47392.55
Authors	Balan, M.,Ishiyama, N.,Marshall, C.B.,Ikura, M. (deposition date: 2017-07-18, release date: 2017-11-15, Last modification date: 2023-10-04)
Primary citation	Sandi, M.J.,Marshall, C.B.,Balan, M.,Coyaud, E.,Zhou, M.,Monson, D.M.,Ishiyama, N.,Chandrakumar, A.A.,La Rose, J.,Couzens, A.L.,Gingras, A.C.,Raught, B.,Xu, W.,Ikura, M.,Morrison, D.K.,Rottapel, R. MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity. Sci Signal, 10:-, 2017 Cited by PubMed: 29089450 DOI: 10.1126/scisignal.aan3286 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation