3DNF

Structure of (E)-4-Hydroxy-3-methyl-but-2-enyl Diphosphate Reductase, the Terminal Enzyme of the Non-Mevalonate Pathway

Summary for 3DNF

• Entry DOI: 10.2210/pdb3dnf/pdb
• Descriptor: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, FE3-S4 CLUSTER, GLYCEROL, ... (4 entities in total)
• Functional Keywords: trilobal strucure, open alpha/beta, iron, iron-sulfur, isoprene biosynthesis, metal-binding, nadp, oxidoreductase
• Biological source: Aquifex aeolicus
• Total number of polymer chains: 2
• Total formula weight: 67215.90

Authors

Rekittke, I. (deposition date: 2008-07-02, release date: 2008-12-30, Last modification date: 2020-09-09)

• Primary citation: Rekittke, I.,Wiesner, J.,Demmer, U.,Warkentin, E.,Xu, W.,Troschke, K.,Hintz, M.,No, J.H.,Duin, E.C.,Oldfield, E.,Jomaa, H.,Ermler, U.; Structure of (E)-4-Hydroxy-3-methyl-but-2-enyl Diphosphate Reductase, the Terminal Enzyme of the Non-Mevalonate Pathway.; J.Am.Chem.Soc., 2008; PubMed: 19035630; DOI: 10.1021/ja806668q

Experimental method

X-RAY DIFFRACTION (1.65 Å)