3DNF

Structure of (E)-4-Hydroxy-3-methyl-but-2-enyl Diphosphate Reductase, the Terminal Enzyme of the Non-Mevalonate Pathway

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	polymer	297	33220.1	2	UniProt (O67625) Pfam (PF02401) In PDB	Aquifex aeolicus	IspH, LytB
2	A, B	FE3-S4 CLUSTER	non-polymer		295.8	2	Chemie (F3S)
3	A, B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4		water	water		18.0	561	Chemie (HOH)

Sequence modifications

A, B: 1 - 289 (UniProt: O67625)

PDB	External Database	Details
Arg 290	-	expression tag
Ser 291	-	expression tag
His 292	-	expression tag
His 293	-	expression tag
His 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66440.1
Non-Polymers*	Number of molecules	4
	Total formula weight	775.8
All*	Total formula weight	67215.9

*Water molecules are not included.