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7E34
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BU of 7e34 by Molmil
Crystal structure of SUN1-Speedy A-CDK2
Descriptor: Cyclin-dependent kinase 2, GLYCEROL, SUN domain-containing protein 1, ...
Authors:Chen, Y, Huang, C, Wu, J, Lei, M.
Deposit date:2021-02-08
Release date:2021-04-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
Nat Commun, 12, 2021
4OV9
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BU of 4ov9 by Molmil
Structure of isopropylmalate synthase binding with alpha-isopropylmalate
Descriptor: (2S)-2-hydroxy-2-(propan-2-yl)butanedioic acid, ZINC ION, isopropylmalate synthase
Authors:Zhang, Z, Wu, J, Wang, C, Zhang, P.
Deposit date:2014-02-20
Release date:2014-08-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition.
J.Biol.Chem., 289, 2014
4OV4
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BU of 4ov4 by Molmil
Isopropylmalate synthase binding with ketoisovalerate
Descriptor: 2-isopropylmalate synthase, 3-METHYL-2-OXOBUTANOIC ACID, ZINC ION
Authors:Zhang, Z, Wu, J, Wang, C, Zhang, P.
Deposit date:2014-02-20
Release date:2014-08-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition.
J.Biol.Chem., 289, 2014
1L8Z
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BU of 1l8z by Molmil
Solution structure of HMG box 5 in human upstream binding factor
Descriptor: upstream binding factor 1
Authors:Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y.
Deposit date:2002-03-22
Release date:2002-06-05
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor
Biochemistry, 42, 2003
1L8Y
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BU of 1l8y by Molmil
Solution structure of HMG box 5 in human upstream binding factor
Descriptor: upstream binding factor 1
Authors:Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y.
Deposit date:2002-03-22
Release date:2002-06-05
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor
Biochemistry, 42, 2003
1LQX
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BU of 1lqx by Molmil
Crystal structure of V45E mutant of cytochrome b5
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, cytochrome b5
Authors:Gan, J.-H, Wu, J, Wang, Z.-Q, Wang, Y.-H, Huang, Z.-X, Xia, Z.-X.
Deposit date:2002-05-14
Release date:2002-09-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of V45E and V45Y mutants and structure comparison of a variety of cytochrome b5 mutants.
Acta Crystallogr.,Sect.D, 58, 2002
1LR6
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BU of 1lr6 by Molmil
Crystal structure of V45Y mutant of cytochrome b5
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, cytochrome b5
Authors:Gan, J.-H, Wu, J, Wang, Z.-Q, Wang, Y.-H, Huang, Z.-X, Xia, Z.-X.
Deposit date:2002-05-15
Release date:2002-09-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of V45E and V45Y mutants and structure comparison of a variety of cytochrome b5 mutants.
Acta Crystallogr.,Sect.D, 58, 2002
1M20
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BU of 1m20 by Molmil
Crystal Structure of F35Y Mutant of Trypsin-solubilized Fragment of Cytochrome b5
Descriptor: Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Yao, P, Wu, J, Wang, Y.-H, Sun, B.-Y, Xia, Z.-X, Huang, Z.-X.
Deposit date:2002-06-20
Release date:2002-09-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallography, CD and kinetic studies revealed the essence of the abnormal behaviors of the cytochrome b5 Phe35-->Tyr mutant.
Eur.J.Biochem., 269, 2002
1MJ3
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BU of 1mj3 by Molmil
Crystal Structure Analysis of rat enoyl-CoA hydratase in complex with hexadienoyl-CoA
Descriptor: ENOYL-COA HYDRATASE, MITOCHONDRIAL, HEXANOYL-COENZYME A
Authors:Bell, A.F, Feng, Y, Hofstein, H.A, Parikh, S, Wu, J, Rudolph, M.J, Kisker, C, Tonge, P.J.
Deposit date:2002-08-26
Release date:2002-09-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Stereoselectivity of Enoyl-CoA Hydratase Results from Preferential Activation of One of Two Bound Substrate Conformers
Chem.Biol., 9, 2002
1M59
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BU of 1m59 by Molmil
Crystal Structure of P40V Mutant of Trypsin-solubilized Fragment of Cytochrome b5
Descriptor: Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Wang, Z.-Q, Wu, J, Wang, Y.-H, Qian, W, Xie, Y, Xia, Z.-X, Huang, Z.-X.
Deposit date:2002-07-09
Release date:2003-03-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Proline40 is essential to maintaining cytochrome b5 stability and its electron transfer with cytochrome c
Chin.J.Chem., 20, 2002
2LQ6
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BU of 2lq6 by Molmil
Solution structure of BRD1 PHD2 finger
Descriptor: Bromodomain-containing protein 1, ZINC ION
Authors:Liu, L, Wu, J.
Deposit date:2012-02-25
Release date:2012-10-24
Method:SOLUTION NMR
Cite:Solution structure of an atypical PHD finger in BRPF2 and its interaction with DNA
J.Struct.Biol., 180, 2012
8HPP
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BU of 8hpp by Molmil
Crystal structure of human INTS3 with SAGE1
Descriptor: Integrator complex subunit 3, Sarcoma antigen 1
Authors:Deng, W, Wu, J, Lei, M.
Deposit date:2022-12-12
Release date:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cancer-testis antigen SAGE1 is a pan-cancer master regulator of RNA polymerase II
To Be Published
2LUY
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BU of 2luy by Molmil
Solution structure of the tandem zinc finger domain of fission yeast Stc1
Descriptor: Meiotic chromosome segregation protein P8B7.28c, ZINC ION
Authors:He, C, Shi, Y, Bayne, E, Wu, J.
Deposit date:2012-06-22
Release date:2013-05-08
Last modified:2013-06-12
Method:SOLUTION NMR
Cite:Structural analysis of Stc1 provides insights into the coupling of RNAi and chromatin modification.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GNE
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BU of 4gne by Molmil
Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-7
Descriptor: Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION
Authors:Li, F, He, C, Wu, J, Shi, Y.
Deposit date:2012-08-17
Release date:2013-01-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
4GND
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BU of 4gnd by Molmil
Crystal Structure of NSD3 tandem PHD5-C5HCH domains
Descriptor: Histone-lysine N-methyltransferase NSD3, ZINC ION
Authors:Li, F, He, C, Wu, J, Shi, Y.
Deposit date:2012-08-17
Release date:2013-01-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
4GNF
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BU of 4gnf by Molmil
Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-15
Descriptor: Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION
Authors:Li, F, He, C, Wu, J, Shi, Y.
Deposit date:2012-08-17
Release date:2013-01-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
4GNG
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BU of 4gng by Molmil
Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3K9me3 peptide
Descriptor: GLYCEROL, Histone H3.3, Histone-lysine N-methyltransferase NSD3, ...
Authors:Li, F, He, C, Wu, J, Shi, Y.
Deposit date:2012-08-17
Release date:2013-01-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
8Q2M
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BU of 8q2m by Molmil
18mer DNA mimic Foldamer with an Aliphatic linker in complex with Sac7d V26A/M29A protein
Descriptor: DNA mimic Foldamer, DNA-binding protein 7b
Authors:Deepak, D, Corvaglia, V, Wu, J, Huc, I.
Deposit date:2023-08-02
Release date:2023-08-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:18mer DNA mimic foldamer with Alphatic linker in complex with Sac7d wild protein.
To Be Published
7D59
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BU of 7d59 by Molmil
cryo-EM structure of human RNA polymerase III in apo state
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M.
Deposit date:2020-09-25
Release date:2021-02-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into transcriptional regulation of human RNA polymerase III.
Nat.Struct.Mol.Biol., 28, 2021
7D58
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BU of 7d58 by Molmil
cryo-EM structure of human RNA polymerase III in elongating state
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M.
Deposit date:2020-09-25
Release date:2021-02-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural insights into transcriptional regulation of human RNA polymerase III.
Nat.Struct.Mol.Biol., 28, 2021
8QPC
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BU of 8qpc by Molmil
18mer DNA mimic Foldamer with an Aromatic linker in complex with Sac7d V26A/M29A protein
Descriptor: DNA-binding protein 7b, N-[2-(2-methyl-1,3-dioxolan-2-yl)phenyl]-2-{[5-(trifluoromethyl)pyridin-2-yl]amino}pyridine-4-carboxamide
Authors:Deepak, D, Corvaglia, V, Wu, J, Huc, I.
Deposit date:2023-10-01
Release date:2023-11-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:DNA-Mimic Foldamer Recognition of a Chromosomal Protein
To Be Published
4LNP
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BU of 4lnp by Molmil
The first SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin
Descriptor: Sorbin and SH3 domain-containing protein 1, Vinculin
Authors:Zhao, D, Li, F, Wu, J, Shi, Y, Zhang, Z, Gong, Q.
Deposit date:2013-07-11
Release date:2014-05-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
4LN2
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BU of 4ln2 by Molmil
The second SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin
Descriptor: Sorbin and SH3 domain-containing protein 1, proline rich peptide
Authors:Zhao, D, Li, F, Wu, J, Shi, Y, Zhang, Z, Gong, Q.
Deposit date:2013-07-11
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
1Q2K
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BU of 1q2k by Molmil
Solution structure of BmBKTx1 a new potassium channel blocker from the Chinese Scorpion Buthus martensi Karsch
Descriptor: Neurotoxin BmK37
Authors:Cai, Z, Xu, C, Xu, Y, Lu, W, Chi, C.W, Shi, Y, Wu, J.
Deposit date:2003-07-25
Release date:2003-09-09
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution Structure of BmBKTx1, a New BK(Ca)(1) Channel Blocker from the Chinese Scorpion Buthus martensi Karsch(,).
Biochemistry, 43, 2004
1RJI
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BU of 1rji by Molmil
Solution Structure of BmKX, a novel potassium channel blocker from the Chinese Scorpion Buthus martensi Karsch
Descriptor: potassium channel toxin KX
Authors:Cai, Z, Wu, J, Xu, Y, Wang, C.-G, Chi, C.-W, Shi, Y.
Deposit date:2003-11-19
Release date:2003-12-09
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:A novel short-chain peptide BmKX from the Chinese scorpion Buthus martensi karsch, sequencing, gene cloning and structure determination
Toxicon, 45, 2005

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