4GNE
Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-7
Summary for 4GNE
Entry DOI | 10.2210/pdb4gne/pdb |
Related | 4GND 4GNF 4GNG |
Descriptor | Histone-lysine N-methyltransferase NSD3, Histone H3.3, ZINC ION, ... (4 entities in total) |
Functional Keywords | zinc finger, transcription, histone, nuclear protein, transferase-nuclear protein complex, transferase/nuclear protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus (By similarity): Q9BZ95 Nucleus: P84243 |
Total number of polymer chains | 2 |
Total formula weight | 13097.31 |
Authors | |
Primary citation | He, C.,Li, F.,Zhang, J.,Wu, J.,Shi, Y. The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition. J.Biol.Chem., 288:4692-4703, 2013 Cited by PubMed: 23269674DOI: 10.1074/jbc.M112.426148 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.47 Å) |
Structure validation
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