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7QWM
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BU of 7qwm by Molmil
TMEM106B filaments with Fold III from Multiple system atrophy (case 17)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWL
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BU of 7qwl by Molmil
TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVC
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BU of 7qvc by Molmil
TMEM106B filaments with Fold I from Alzheimer's disease (case 1)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-21
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QJX
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BU of 7qjx by Molmil
In vitro assembled 297-394 tau filaments, 700 rpm (34b)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-03-23
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKJ
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BU of 7qkj by Molmil
In vitro assembled 266/297 - 391 tau filaments with MgCl2 and NaCl (14b)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-03-23
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
8ORG
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BU of 8org by Molmil
Cryo-EM structure of SH-SY5Y seeded with filaments from corticobasal degeneration extracts (Type II)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-13
Release date:2023-04-26
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Febs Open Bio, 13, 2023
8ORE
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BU of 8ore by Molmil
Cryo-EM structure of SH-SY5Y seeded with filaments from Alzheimer's Disease
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-13
Release date:2023-04-26
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Febs Open Bio, 13, 2023
8ORF
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BU of 8orf by Molmil
Cryo-EM structure of SH-SY5Y seeded with filaments from corticobasal degeneration extracts
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-13
Release date:2023-04-26
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Febs Open Bio, 13, 2023
8OT9
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BU of 8ot9 by Molmil
CTE typeIII tau filament from Guam ALS/PDC
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTF
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BU of 8otf by Molmil
Ab typeII filament from Guam ALS/PDC
Descriptor: Amyloid-beta precursor protein
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTG
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BU of 8otg by Molmil
CTE typeI tau filament from Kii ALS/PDC
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OT6
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BU of 8ot6 by Molmil
CTE typeI tau filament from Guam ALS/PDC
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTE
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BU of 8ote by Molmil
TMEM106B Fold I-d filament from Guam ALS/PDC
Descriptor: Transmembrane protein 106B
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTD
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BU of 8otd by Molmil
TMEM106B Fold1-s filament from Guam ALS/PDC
Descriptor: Transmembrane protein 106B
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTC
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BU of 8otc by Molmil
CTE typeII tau filament from Guam ALS/PDC
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8P34
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BU of 8p34 by Molmil
Tau filaments extracted from human brain with the DeltaK281 mutation in MAPT
Descriptor: Microtubule-associated protein tau
Authors:Schweighauser, M, Garringer, H.J, Klingstedt, T, Masuda-Suzukake, M, Murrell, J.R, Vidal, R, Scheres, S.H.W, Goedert, M, Ghetti, B, Newell, K.L.
Deposit date:2023-05-17
Release date:2023-07-05
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Mutation ∆K281 in MAPT causes Pick's disease.
Acta Neuropathol, 146, 2023
8PPO
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BU of 8ppo by Molmil
First Intermediate Amyloid (FIA) - Tau
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W, Goedert, M, Li, D.
Deposit date:2023-07-07
Release date:2023-08-02
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q2J
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BU of 8q2j by Molmil
Tau - AD-MIA2
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-02
Release date:2023-08-30
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2.23 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q27
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BU of 8q27 by Molmil
Tau: AD-MIA1
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W, Goedert, M, Li, D.
Deposit date:2023-08-01
Release date:2023-08-30
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2.02 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q2K
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BU of 8q2k by Molmil
Tau - AD-MIA3
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-02
Release date:2023-08-30
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q2L
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BU of 8q2l by Molmil
Tau - AD-MIA4
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-02
Release date:2023-09-20
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8OTJ
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BU of 8otj by Molmil
PHF tau filament from Kii ALS/PDC
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTI
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BU of 8oti by Molmil
CTE typeIII tau filament
Descriptor: Microtubule-associated protein tau
Authors:Tetter, S, Qi, C, Ryskeldi-Falcon, B, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTH
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BU of 8oth by Molmil
TypeII tau filament from Kii ALS/PDC
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8Q7M
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BU of 8q7m by Molmil
Tau - AD-MIA7 (tau intermediate amyloid)
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-16
Release date:2023-08-30
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024

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PDB entries from 2024-04-24

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