7QJX

In vitro assembled 297-394 tau filaments, 700 rpm (34b)

Summary for 7QJX

• Entry DOI: 10.2210/pdb7qjx/pdb
• EMDB information: 14025
• Descriptor: Microtubule-associated protein tau (1 entity in total)
• Functional Keywords: alzheimer's disease, amyloid, tau, neurodegeneration, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 12
• Total formula weight: 551038.45

Authors

Lovestam, S.,Scheres, S.H.W. (deposition date: 2021-12-17, release date: 2022-03-23)

• Primary citation: Lovestam, S.,Koh, F.A.,van Knippenberg, B.,Kotecha, A.,Murzin, A.G.,Goedert, M.,Scheres, S.H.W.; Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.; Elife, 11:-, 2022; PubMed: 35244536; DOI: 10.7554/eLife.76494

Experimental method

ELECTRON MICROSCOPY (2.99 Å)