4LZO
| Crystal structure of human PRS1 A87T mutant | Descriptor: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | Authors: | Chen, P, Teng, M, Li, X. | Deposit date: | 2013-07-31 | Release date: | 2015-02-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations Plos One, 10, 2015
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4LWO
| Crystal structure of PRMT6 | Descriptor: | Arginine N-methyltransferase, putative | Authors: | Zhu, Y, Wang, C, Shi, Y, Teng, M. | Deposit date: | 2013-07-28 | Release date: | 2014-02-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.203 Å) | Cite: | Crystal Structure of Arginine Methyltransferase 6 from Trypanosoma brucei Plos One, 9, 2014
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4LYG
| Crystal structure of human PRS1 E43T mutant | Descriptor: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | Authors: | Chen, P, Teng, M, Li, X. | Deposit date: | 2013-07-31 | Release date: | 2015-02-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations Plos One, 10, 2015
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4LZN
| Crystal structure of human PRS1 D65N mutant | Descriptor: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | Authors: | Chen, P, Teng, M, Li, X. | Deposit date: | 2013-07-31 | Release date: | 2015-02-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations Plos One, 10, 2015
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4M0P
| Crystal structure of human PRS1 M115T mutant | Descriptor: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | Authors: | Chen, P, Teng, M, Li, X. | Deposit date: | 2013-08-01 | Release date: | 2015-02-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations Plos One, 10, 2015
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4M0U
| crystal structure of human PRS1 Q133P mutant | Descriptor: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | Authors: | Chen, P, Teng, M, Li, X. | Deposit date: | 2013-08-02 | Release date: | 2015-02-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations Plos One, 10, 2015
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7CLD
| Crystal structure of T2R-TTL-Cevipabulin complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-[2,6-bis(fluoranyl)-4-[3-(methylamino)propoxy]phenyl]-5-chloranyl-N-[(2S)-1,1,1-tris(fluoranyl)propan-2-yl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, CALCIUM ION, ... | Authors: | Chen, L.J, Chen, Q, Yu, Y, Yang, J.H. | Deposit date: | 2020-07-20 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.611 Å) | Cite: | Cevipabulin-tubulin complex reveals a novel agent binding site on alpha-tubulin with tubulin degradation effect. Sci Adv, 7, 2021
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7DP8
| Crystal structure of T2R-TTL-Cevipabulin-eribulin complex | Descriptor: | (1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,33R,35R,36S)-20-[(2S)-3-amino-2-hydroxypropyl]-21-methoxy-14-methyl-8,15-dimethylidene-2,19,30,34,37,39,40,41-octaoxanonacyclo[24.9.2.1~3,32~.1~3,33~.1~6,9~.1~12,16~.0~18,22~.0~29,36~.0~31,35~]hentetracontan-24-one (non-preferred name), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-[2,6-bis(fluoranyl)-4-[3-(methylamino)propoxy]phenyl]-5-chloranyl-N-[(2S)-1,1,1-tris(fluoranyl)propan-2-yl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, ... | Authors: | Chen, L.J, Chen, Q, Yu, Y, Yang, J.H. | Deposit date: | 2020-12-18 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.446 Å) | Cite: | Cevipabulin-tubulin complex reveals a novel agent binding site on alpha-tubulin with tubulin degradation effect. Sci Adv, 7, 2021
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5CMW
| Crystal structure of yeast Ent5 N-terminal domain-soaked in KI | Descriptor: | Epsin-5, GLYCEROL, IODIDE ION | Authors: | Zhang, F, Song, Y, Li, X, Teng, M.K. | Deposit date: | 2015-07-17 | Release date: | 2016-07-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and functional insight into the N-terminal domain of the clathrin adaptor Ent5 from Saccharomyces cerevisiae Biochem.Biophys.Res.Commun., 477, 2016
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5CMY
| Crystal structure of yeast Ent5 N-terminal domain-native | Descriptor: | Epsin-5, GLYCEROL | Authors: | Zhang, F, Song, Y, Li, X, Teng, M.K. | Deposit date: | 2015-07-17 | Release date: | 2016-07-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structural and functional insight into the N-terminal domain of the clathrin adaptor Ent5 from Saccharomyces cerevisiae Biochem.Biophys.Res.Commun., 477, 2016
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5DIK
| Crystal structure of apo-lpg0406, a carboxymuconolactone decarboxylase family protein from Legionella pneumophila | Descriptor: | Alkyl hydroperoxide reductase AhpD | Authors: | Chen, X, Gong, X, Zhang, N, Ge, H. | Deposit date: | 2015-09-01 | Release date: | 2015-10-14 | Last modified: | 2016-01-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of lpg0406, a carboxymuconolactone decarboxylase family protein possibly involved in antioxidative response from Legionella pneumophila Protein Sci., 24, 2015
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5DIP
| Crystal structure of lpg0406 in reduced form from Legionella pneumophila | Descriptor: | Alkyl hydroperoxide reductase AhpD, GLYCEROL, SODIUM ION | Authors: | Chen, X, Gong, X, Zhang, N, Ge, H. | Deposit date: | 2015-09-01 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.097 Å) | Cite: | Structure of lpg0406, a carboxymuconolactone decarboxylase family protein possibly involved in antioxidative response from Legionella pneumophila Protein Sci., 24, 2015
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6K9V
| Crystal structure of tubulin in complex with inhibitor D64 | Descriptor: | (5-methoxy-1H-indol-2-yl)-phenyl-methanone, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Yu, Y, Chen, Q. | Deposit date: | 2019-06-18 | Release date: | 2019-08-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.543 Å) | Cite: | Structural insights into the design of indole derivatives as tubulin polymerization inhibitors. Febs Lett., 594, 2020
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5ERG
| Crystal structure of the two-subunit tRNA m1A58 methyltransferase TRM6-TRM61 in complex with SAM | Descriptor: | S-ADENOSYLMETHIONINE, tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 | Authors: | Zhu, Y, Wang, M, Wang, C, Fan, X, Jiang, X, Teng, M, Li, X. | Deposit date: | 2015-11-14 | Release date: | 2016-09-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae. Sci Rep, 6, 2016
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5EQJ
| Crystal structure of the two-subunit tRNA m1A58 methyltransferase from Saccharomyces cerevisiae | Descriptor: | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 | Authors: | Zhu, Y, Wang, M, Wang, C, Fan, X, Jiang, X, Teng, M, Li, X. | Deposit date: | 2015-11-13 | Release date: | 2016-09-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae. Sci Rep, 6, 2016
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3GYO
| Se-Met Rtt106p | Descriptor: | Histone chaperone RTT106 | Authors: | Liu, Y, Huang, H, Shi, Y, Teng, M. | Deposit date: | 2009-04-04 | Release date: | 2009-12-08 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural analysis of Rtt106p reveals a DNA-binding role required for heterochromatin silencing J.Biol.Chem., 285, 2010
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3GYP
| Rtt106p | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Histone chaperone RTT106 | Authors: | Liu, Y, Huang, H, Shi, Y, Teng, M. | Deposit date: | 2009-04-04 | Release date: | 2009-12-08 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.406 Å) | Cite: | Structural analysis of Rtt106p reveals a DNA-binding role required for heterochromatin silencing J.Biol.Chem., 285, 2010
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7CDA
| Crystal structure of T2R-TTL-PAC complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | Authors: | Chen, L.J, Chen, Q, Yu, Y, Yang, J.H. | Deposit date: | 2020-06-19 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.659 Å) | Cite: | Small Molecules Promote Selective Denaturation and Degradation of Tubulin Heterodimers through a Low-Barrier Hydrogen Bond. J.Med.Chem., 65, 2022
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7CE8
| Crystal structure of T2R-TTL-Compound11 complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | Authors: | Chen, L.J, Chen, Q, Yu, Y, Yang, J.H. | Deposit date: | 2020-06-22 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.725 Å) | Cite: | Small Molecules Promote Selective Denaturation and Degradation of Tubulin Heterodimers through a Low-Barrier Hydrogen Bond. J.Med.Chem., 65, 2022
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7CEK
| Crystal structure of T2R-TTL-BML-284 complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Chen, L.J, Chen, Q, Yu, Y, Yang, J.H. | Deposit date: | 2020-06-23 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.696 Å) | Cite: | Small Molecules Promote Selective Denaturation and Degradation of Tubulin Heterodimers through a Low-Barrier Hydrogen Bond. J.Med.Chem., 65, 2022
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7CE6
| Crystal structure of T2R-TTL-Compound9 complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | Authors: | Chen, L.J, Chen, Q, Yu, Y, Yang, J.H. | Deposit date: | 2020-06-22 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.695 Å) | Cite: | Small Molecules Promote Selective Denaturation and Degradation of Tubulin Heterodimers through a Low-Barrier Hydrogen Bond. J.Med.Chem., 65, 2022
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4FZ7
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4HYS
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4HYU
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6AI9
| Cab2 mutant-H337A complex with phosphopantothenate | Descriptor: | N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanine, Phosphopantothenate--cysteine ligase CAB2 | Authors: | Zheng, P, Zhu, Z. | Deposit date: | 2018-08-22 | Release date: | 2019-03-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae. J. Mol. Biol., 431, 2019
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