6K9V

Crystal structure of tubulin in complex with inhibitor D64

Summary for 6K9V

• Entry DOI: 10.2210/pdb6k9v/pdb
• Descriptor: Tubulin alpha-1B chain, CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total)
• Functional Keywords: tubulin, inhibitor, complex, cell cycle, structural protein
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 6
• Total formula weight: 264682.33

Authors

Yu, Y.,Chen, Q. (deposition date: 2019-06-18, release date: 2019-08-28, Last modification date: 2023-11-22)

• Primary citation: Li, Y.,Yang, J.,Niu, L.,Hu, D.,Li, H.,Chen, L.,Yu, Y.,Chen, Q.; Structural insights into the design of indole derivatives as tubulin polymerization inhibitors.; Febs Lett., 594:199-204, 2020; PubMed: 31369682; DOI: 10.1002/1873-3468.13566

Experimental method

X-RAY DIFFRACTION (2.543 Å)