4M0P
Crystal structure of human PRS1 M115T mutant
Summary for 4M0P
Entry DOI | 10.2210/pdb4m0p/pdb |
Related | 4LYG 4LZO 4LZP 4M0U |
Descriptor | Ribose-phosphate pyrophosphokinase 1, SULFATE ION (3 entities in total) |
Functional Keywords | prs1, prpp synthesis enzyme, atp r5p, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 72416.94 |
Authors | |
Primary citation | Chen, P.,Liu, Z.,Wang, X.,Peng, J.,Sun, Q.,Li, J.,Wang, M.,Niu, L.,Zhang, Z.,Cai, G.,Teng, M.,Li, X. Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations Plos One, 10:e0120304-e0120304, 2015 Cited by PubMed: 25781187DOI: 10.1371/journal.pone.0120304 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.11 Å) |
Structure validation
Download full validation report