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6UCF
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BU of 6ucf by Molmil
N123-VRC34_pI4 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Descriptor: HIV fusion peptide, N123-VRC34_pI4 heavy chain, N123-VRC34_pI4 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2019-09-16
Release date:2020-03-18
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.
Cell Host Microbe, 27, 2020
6VIL
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BU of 6vil by Molmil
Crystal structure of mouse BAHCC1 BAH domain in complex with H3K27me3
Descriptor: BAH and coiled-coil domain-containing protein 1, Histone H3.1
Authors:Song, J, Lu, J.
Deposit date:2020-01-13
Release date:2020-09-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis.
Nat.Genet., 52, 2020
4YES
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BU of 4yes by Molmil
Thrombin in complex with (S)-(4-chloro-2-((1-(5-methyl-1H-pyrrole-2-carbonyl)pyrrolidine-2-carboxamido)methyl)phenyl)methanaminium
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hirudin, ...
Authors:Orth, P.
Deposit date:2015-02-24
Release date:2015-06-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Improved Stability of Proline-Derived Direct Thrombin Inhibitors through Hydroxyl to Heterocycle Replacement.
Acs Med.Chem.Lett., 6, 2015
7MHS
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BU of 7mhs by Molmil
Structure of p97 (subunits A to E) with substrate engaged
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Xu, Y, Han, H, Cooney, I, Hill, C.P, Shen, P.S.
Deposit date:2021-04-15
Release date:2022-05-11
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Active conformation of the p97-p47 unfoldase complex.
Nat Commun, 13, 2022
7RW2
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BU of 7rw2 by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 5-7 in complex with prefusion SARS-CoV-2 spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-7 heavy chain, ...
Authors:Cerutti, G, Shapiro, L.
Deposit date:2021-08-19
Release date:2021-09-01
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain.
Cell Rep, 37, 2021
7L2C
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BU of 7l2c by Molmil
Crystallographic structure of neutralizing antibody 2-51 in complex with SARS-CoV-2 spike N-terminal domain (NTD)
Descriptor: 2-51 heavy chain, 2-51 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cerutti, G, Reddem, E.R, Shapiro, L.
Deposit date:2020-12-16
Release date:2021-02-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
2P15
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BU of 2p15 by Molmil
Crystal structure of the ER alpha ligand binding domain with the agonist ortho-trifluoromethylphenylvinyl estradiol
Descriptor: (17BETA)-17-{(E)-2-[2-(TRIFLUOROMETHYL)PHENYL]VINYL}ESTRA-1(10),2,4-TRIENE-3,17-DIOL, Estrogen receptor, GRIP peptide
Authors:Bruning, J.B, Nettles, K.W, Greene, G.L, Kim, Y.
Deposit date:2007-03-02
Release date:2007-05-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural plasticity in the oestrogen receptor ligand-binding domain.
Embo Rep., 8, 2007
7L2E
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BU of 7l2e by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 4-18 in complex with prefusion SARS-CoV-2 spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-18 heavy chain, ...
Authors:Cerutti, G, Shapiro, L.
Deposit date:2020-12-16
Release date:2021-03-24
Last modified:2021-05-26
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
7L2F
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BU of 7l2f by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 5-24 in complex with prefusion SARS-CoV-2 spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-24 heavy chain, ...
Authors:Cerutti, G, Shapiro, L.
Deposit date:2020-12-16
Release date:2021-03-24
Last modified:2021-05-26
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
7L2D
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BU of 7l2d by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 1-87 in complex with prefusion SARS-CoV-2 spike glycoprotein
Descriptor: 1-87 heavy chain, 1-87 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cerutti, G, Shapiro, L.
Deposit date:2020-12-16
Release date:2021-03-24
Last modified:2021-05-26
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
7L58
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BU of 7l58 by Molmil
Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab H4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab H4 variable domain heavy chain, ...
Authors:Rapp, M, Shapiro, L.
Deposit date:2020-12-21
Release date:2021-04-14
Last modified:2021-04-21
Method:ELECTRON MICROSCOPY (5.07 Å)
Cite:Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class.
Cell Rep, 35, 2021
7L57
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BU of 7l57 by Molmil
Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-15
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rapp, M, Shapiro, L.
Deposit date:2020-12-21
Release date:2021-04-14
Last modified:2021-04-21
Method:ELECTRON MICROSCOPY (5.87 Å)
Cite:Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class.
Cell Rep, 35, 2021
7L56
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BU of 7l56 by Molmil
Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-43
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2-43 variable domain heavy chain, ...
Authors:Rapp, M, Shapiro, L.
Deposit date:2020-12-21
Release date:2021-04-14
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class.
Cell Rep, 35, 2021
7LMM
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BU of 7lmm by Molmil
Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me2
Descriptor: DNA (cytosine-5)-methyltransferase 1,DNA (cytosine-5)-methyltransferase 1, Histone H4, ZINC ION
Authors:Ren, W, Song, J.
Deposit date:2021-02-05
Release date:2021-02-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Nat Commun, 12, 2021
7LMK
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BU of 7lmk by Molmil
Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me3
Descriptor: DNA (cytosine-5)-methyltransferase 1, Histone H4, ZINC ION
Authors:Ren, W, Song, J.
Deposit date:2021-02-05
Release date:2021-02-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.647 Å)
Cite:DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Nat Commun, 12, 2021
7LQV
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BU of 7lqv by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 4-8 Fab in complex with SARS-CoV-2 S2P spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-8 Heavy Chain, 4-8 Light chain, ...
Authors:Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L.
Deposit date:2021-02-15
Release date:2021-03-24
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite
Cell Host Microbe, 2021
7LQW
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BU of 7lqw by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 2-17 Fab in complex with SARS-CoV-2 S2P spike
Descriptor: 2-17 Heavy Chain, 2-17 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L.
Deposit date:2021-02-15
Release date:2021-03-24
Last modified:2021-05-26
Method:ELECTRON MICROSCOPY (4.47 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
3PMT
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BU of 3pmt by Molmil
Crystal structure of the Tudor domain of human Tudor domain-containing protein 3
Descriptor: TETRAETHYLENE GLYCOL, Tudor domain-containing protein 3
Authors:Lam, R, Bian, C.B, Guo, Y.H, Xu, C, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2010-11-18
Release date:2010-12-01
Last modified:2023-05-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of TDRD3 and Methyl-Arginine Binding Characterization of TDRD3, SMN and SPF30.
Plos One, 7, 2012
8DS8
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BU of 8ds8 by Molmil
Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide
Descriptor: Histone H3.1, Trinucleotide repeat-containing gene 18 protein
Authors:Song, J.K, Lu, J.W.
Deposit date:2022-07-21
Release date:2023-08-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons.
Nature, 623, 2023
6U8X
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BU of 6u8x by Molmil
Crystal structure of DNMT3B-DNMT3L in complex with CpApG DNA
Descriptor: CpApG DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
Authors:Gao, L, Song, J.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.95063877 Å)
Cite:Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.
Nat Commun, 11, 2020
6U8P
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BU of 6u8p by Molmil
Crystal structure of DNMT3B-DNMT3L in complex with CpGpA DNA
Descriptor: CpGpA DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
Authors:Gao, L, Song, J.
Deposit date:2019-09-05
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.
Nat Commun, 11, 2020
6U8V
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BU of 6u8v by Molmil
Crystal structure of DNMT3B-DNMT3L in complex with CpGpT DNA
Descriptor: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
Authors:Gao, L, Zhang, Z.M, Song, J.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.
Nat Commun, 11, 2020
6U8W
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BU of 6u8w by Molmil
Crystal structure of DNMT3B(K777A)-DNMT3L in complex with CpGpT DNA
Descriptor: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
Authors:Gao, L, Zhang, Z.M, Song, J.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.94891548 Å)
Cite:Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.
Nat Commun, 11, 2020
3WLW
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BU of 3wlw by Molmil
Molecular Architecture of the ErbB2 Extracellular Domain Homodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody H Chain, ...
Authors:Hu, S, Lou, Z.Y, Guo, Y.J.
Deposit date:2013-11-15
Release date:2015-05-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.088 Å)
Cite:Molecular architecture of the ErbB2 extracellular domain homodimer.
Oncotarget, 6, 2015
7PBG
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BU of 7pbg by Molmil
4-ethylphenol oxidase from Gulosibacter chungangensis: native structure
Descriptor: CHLORIDE ION, FAD-binding oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Alvigini, L, Mattevi, A.
Deposit date:2021-08-02
Release date:2021-09-29
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery, Biocatalytic Exploration and Structural Analysis of a 4-Ethylphenol Oxidase from Gulosibacter chungangensis.
Chembiochem, 22, 2021

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