7RW2
Cryo-EM structure of NTD-directed neutralizing antibody 5-7 in complex with prefusion SARS-CoV-2 spike glycoprotein
Replaces: 7N01Summary for 7RW2
Entry DOI | 10.2210/pdb7rw2/pdb |
EMDB information | 24708 |
Descriptor | Spike glycoprotein, 5-7 heavy chain, 5-7 light chain, ... (5 entities in total) |
Functional Keywords | neutralizing antibody, fusion protein, spike glycoprotein, covid-19, n-terminal domain, ntd, 5-7, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 9 |
Total formula weight | 591078.99 |
Authors | Cerutti, G.,Shapiro, L. (deposition date: 2021-08-19, release date: 2021-09-01, Last modification date: 2022-11-30) |
Primary citation | Cerutti, G.,Guo, Y.,Wang, P.,Nair, M.S.,Wang, M.,Huang, Y.,Yu, J.,Liu, L.,Katsamba, P.S.,Bahna, F.,Reddem, E.R.,Kwong, P.D.,Ho, D.D.,Sheng, Z.,Shapiro, L. Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain. Cell Rep, 37:109928-109928, 2021 Cited by PubMed: 34706271DOI: 10.1016/j.celrep.2021.109928 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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