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7RW2

Cryo-EM structure of NTD-directed neutralizing antibody 5-7 in complex with prefusion SARS-CoV-2 spike glycoprotein

Replaces:  7N01
Summary for 7RW2
Entry DOI10.2210/pdb7rw2/pdb
EMDB information24708
DescriptorSpike glycoprotein, 5-7 heavy chain, 5-7 light chain, ... (5 entities in total)
Functional Keywordsneutralizing antibody, fusion protein, spike glycoprotein, covid-19, n-terminal domain, ntd, 5-7, viral protein-immune system complex, viral protein/immune system
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains9
Total formula weight591078.99
Authors
Cerutti, G.,Shapiro, L. (deposition date: 2021-08-19, release date: 2021-09-01, Last modification date: 2022-11-30)
Primary citationCerutti, G.,Guo, Y.,Wang, P.,Nair, M.S.,Wang, M.,Huang, Y.,Yu, J.,Liu, L.,Katsamba, P.S.,Bahna, F.,Reddem, E.R.,Kwong, P.D.,Ho, D.D.,Sheng, Z.,Shapiro, L.
Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain.
Cell Rep, 37:109928-109928, 2021
Cited by
PubMed: 34706271
DOI: 10.1016/j.celrep.2021.109928
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.5 Å)
Structure validation

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