5M95
 
 | | STAPHYLOCOCCUS CAPITIS DIVALENT METAL ION TRANSPORTER (DMT) IN COMPLEX WITH MANGANESE | | 分子名称: | CAMELID ANTIBODY FRAGMENT, NANOBODY, Divalent metal cation transporter MntH, ... | | 著者 | Ehrnstorfer, I.A, Geertsma, E.R, Pardon, E, Steyaert, J, Dutzler, R. | | 登録日 | 2016-10-31 | | 公開日 | 2016-11-30 | | 最終更新日 | 2019-09-25 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Crystal Structure Of A Slc11 (Nramp) Transporter Reveals The Basis For Transition-Metal Ion Transport.
Nat.Struct.Mol.Biol., 21, 2014
|
|
5HEW
 | |
5HEJ
 | |
5HEO
 | |
5HEU
 | |
5HEH
 | |
2VL0
 | |
7ZK3
 | | Structure of 1PBC- and calcium-bound mTMEM16A(ac) chloride channel at 2.85 A resolution | | 分子名称: | 1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile, Anoctamin-1, CALCIUM ION | | 著者 | Lam, A.K.M, Rutz, S, Dutzler, R. | | 登録日 | 2022-04-12 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC.
Nat Commun, 13, 2022
|
|
8B40
 | |
8B41
 | |
8B42
 | |
8B8J
 | | Cryo-EM structure of Ca2+-bound mTMEM16F F518H mutant in Digitonin | | 分子名称: | Anoctamin-6, CALCIUM ION | | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-04 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
|
|
8B8K
 | | Cryo-EM structure of Ca2+-bound mTMEM16F N562A mutant in Digitonin closed/closed | | 分子名称: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Anoctamin-6, CALCIUM ION | | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-04 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
|
|
8BC0
 | | Cryo-EM structure of Ca2+-bound mTMEM16F F518A Q623A mutant in GDN open/closed | | 分子名称: | Anoctamin-6, CALCIUM ION | | 著者 | Arndt, M, Alvadia, C, Straub, M, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-14 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
|
|
8B8M
 | | Cryo-EM structure of Ca2+-bound mTMEM16F N562A mutant in Digitonin open/closed | | 分子名称: | Anoctamin-6, CALCIUM ION | | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-04 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
|
|
8B8G
 | | Cryo-EM structure of Ca2+-free mTMEM16F F518H mutant in Digitonin | | 分子名称: | Anoctamin-6 | | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-04 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
|
|
8BC1
 | | Cryo-EM Structure of Ca2+-bound mTMEM16F F518A_Q623A mutant in GDN | | 分子名称: | Anoctamin-6,mTMEM16F, CALCIUM ION | | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-14 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
|
|
8BEN
 | |
8B8Q
 | | Structure of mTMEM16F in lipid Nanodiscs in the presence of Ca2+ | | 分子名称: | Anoctamin-6, CALCIUM ION | | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-04 | | 公開日 | 2022-12-21 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
|
|
8C03
 | | Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy12 in outward-facing conformation | | 分子名称: | 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, Solute carrier family 40 member 1 | | 著者 | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | 登録日 | 2022-12-15 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | | 主引用文献 | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
|
|
8BZY
 | | Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy3 in occluded conformation | | 分子名称: | 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, DIUNDECYL PHOSPHATIDYL CHOLINE, Solute carrier family 40 member 1, ... | | 著者 | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | 登録日 | 2022-12-15 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
|
|
8C02
 | | Structure of SLC40/ferroportin in complex with synthetic nanobody Sy3 in occluded conformation | | 分子名称: | Solute carrier family 40 member 1, Sybody3 | | 著者 | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | 登録日 | 2022-12-15 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (4.09 Å) | | 主引用文献 | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
|
|
5NL2
 | | cryo-EM structure of the mTMEM16A ion channel at 6.6 A resolution. | | 分子名称: | Anoctamin-1 | | 著者 | Paulino, C, Neldner, Y, Lam, K.M, Kalienkova, V, Brunner, J.D, Schenck, S, Dutzler, R. | | 登録日 | 2017-04-03 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A.
Elife, 6, 2017
|
|
5OYB
 | | Structure of calcium-bound mTMEM16A chloride channel at 3.75 A resolution | | 分子名称: | Anoctamin-1, CALCIUM ION | | 著者 | Paulino, C, Kalienkova, V, Lam, K.M, Neldner, Y, Dutzler, R. | | 登録日 | 2017-09-08 | | 公開日 | 2017-12-20 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM.
Nature, 552, 2017
|
|
5OYG
 | | Structure of calcium-free mTMEM16A chloride channel at 4.06 A resolution | | 分子名称: | Anoctamin-1 | | 著者 | Paulino, C, Kalienkova, V, Lam, K.M, Neldner, Y, Dutzler, R. | | 登録日 | 2017-09-08 | | 公開日 | 2017-12-20 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (4.06 Å) | | 主引用文献 | Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM.
Nature, 552, 2017
|
|
