8B8G
Cryo-EM structure of Ca2+-free mTMEM16F F518H mutant in Digitonin
Summary for 8B8G
| Entry DOI | 10.2210/pdb8b8g/pdb |
| EMDB information | 15913 |
| Descriptor | Anoctamin-6 (1 entity in total) |
| Functional Keywords | lipid transport, lipid scrambling, ion channel, plasma membrane, blood clotting, exocytosis, membrane fusion, membrane protein |
| Biological source | Mus musculus (house mouse) |
| Total number of polymer chains | 2 |
| Total formula weight | 226909.20 |
| Authors | Arndt, M.,Alvadia, C.,Straub, M.S.,Clerico-Mosina, V.,Paulino, C.,Dutzler, R. (deposition date: 2022-10-04, release date: 2022-11-16) |
| Primary citation | Arndt, M.,Alvadia, C.,Straub, M.S.,Clerico Mosina, V.,Paulino, C.,Dutzler, R. Structural basis for the activation of the lipid scramblase TMEM16F. Nat Commun, 13:6692-6692, 2022 Cited by PubMed: 36335104DOI: 10.1038/s41467-022-34497-x PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.39 Å) |
Structure validation
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