8B41
Structure of heteromeric LRRC8A/C (1:1 co-transfected) Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1
Summary for 8B41
| Entry DOI | 10.2210/pdb8b41/pdb |
| Related | 8B41 8B42 8BEN |
| EMDB information | 15835 15836 15837 15838 15839 15840 15841 |
| Descriptor | Volume-regulated anion channel subunit LRRC8A, Volume-regulated anion channel subunit LRRC8C, Synthetic nanobody Sb1 (3 entities in total) |
| Functional Keywords | ion channel, volume-regulated anion channel, membrane protein |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 10 |
| Total formula weight | 619632.55 |
| Authors | Sawicka, M.,Dutzler, R. (deposition date: 2022-09-19, release date: 2022-12-14, Last modification date: 2023-02-01) |
| Primary citation | Rutz, S.,Deneka, D.,Dittmann, A.,Sawicka, M.,Dutzler, R. Structure of a volume-regulated heteromeric LRRC8A/C channel. Nat.Struct.Mol.Biol., 30:52-61, 2023 Cited by PubMed: 36522427DOI: 10.1038/s41594-022-00899-0 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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