8BC0
Cryo-EM structure of Ca2+-bound mTMEM16F F518A Q623A mutant in GDN open/closed
Summary for 8BC0
| Entry DOI | 10.2210/pdb8bc0/pdb |
| EMDB information | 15958 |
| Descriptor | Anoctamin-6, CALCIUM ION (2 entities in total) |
| Functional Keywords | membrane protein, lipid scramblase, ion channel |
| Biological source | Mus musculus (house mouse) |
| Total number of polymer chains | 2 |
| Total formula weight | 226901.44 |
| Authors | Arndt, M.,Alvadia, C.,Straub, M.,Clerico-Mosina, V.,Paulino, C.,Dutzler, R. (deposition date: 2022-10-14, release date: 2022-11-16) |
| Primary citation | Arndt, M.,Alvadia, C.,Straub, M.S.,Clerico Mosina, V.,Paulino, C.,Dutzler, R. Structural basis for the activation of the lipid scramblase TMEM16F. Nat Commun, 13:6692-6692, 2022 Cited by PubMed: 36335104DOI: 10.1038/s41467-022-34497-x PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.09 Å) |
Structure validation
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