1FUF
 
 | | CRYSTAL STRUCTURE OF A 14BP RNA OLIGONUCLEOTIDE CONTAINING DOUBLE UU BULGES: A NOVEL INTRAMOLECULAR U*(AU) BASE TRIPLE | | 分子名称: | (5'-R(*GP*GP*UP*AP*UP*UP*UP*CP*GP*GP*UP*AP*(CBR)P*C)-3'), MAGNESIUM ION, SPERMINE | | 著者 | Deng, J, Xiong, Y, Sudarsanakumar, C, Shi, K, Sundaralingam, M. | | 登録日 | 2000-09-15 | | 公開日 | 2001-11-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structures of two forms of a 14-mer RNA/DNA chimer duplex with double UU bulges: a novel intramolecular U*(A x U) base triple.
RNA, 7, 2001
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1XDN
 | | High resolution crystal structure of an editosome enzyme from trypanosoma brucei: RNA editing ligase 1 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA editing ligase MP52 | | 著者 | Deng, J, Schnaufer, A, Salavati, R, Stuart, K.D, Hol, W.G. | | 登録日 | 2004-09-07 | | 公開日 | 2004-12-07 | | 最終更新日 | 2014-09-10 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | High resolution crystal structure of a key editosome enzyme from Trypanosoma brucei: RNA editing ligase 1.
J.Mol.Biol., 343, 2004
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2B51
 | | Structural Basis for UTP Specificity of RNA Editing TUTases from Trypanosoma Brucei | | 分子名称: | MANGANESE (II) ION, RNA editing complex protein MP57, URIDINE 5'-TRIPHOSPHATE | | 著者 | Deng, J, Ernst, N.L, Turley, S, Stuart, K.D, Hol, W.G. | | 登録日 | 2005-09-27 | | 公開日 | 2005-11-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei.
Embo J., 24, 2005
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2B4V
 | | Structural Basis for UTP Specificity of RNA Editing TUTases From Trypanosoma Brucei | | 分子名称: | POTASSIUM ION, RNA editing complex protein MP57 | | 著者 | Deng, J, Ernst, N.L, Turley, S, Stuart, K.D, Hol, W.G. | | 登録日 | 2005-09-26 | | 公開日 | 2005-11-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei.
Embo J., 24, 2005
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2B56
 | | Structural Basis for UTP Specificity of RNA Editing TUTases From Trypanosoma Brucei | | 分子名称: | MAGNESIUM ION, RNA editing complex protein MP57, URIDINE 5'-TRIPHOSPHATE, ... | | 著者 | Deng, J, Ernst, N.L, Turley, S, Stuart, K.D, Hol, W.G. | | 登録日 | 2005-09-27 | | 公開日 | 2005-11-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei.
Embo J., 24, 2005
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2ZEJ
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7V9E
 | | Crystal structure of a methyl transferase ribozyme | | 分子名称: | BARIUM ION, GUANINE, RNA (68-MER), ... | | 著者 | Deng, J, Lilley, D.M.J, Huang, L. | | 登録日 | 2021-08-25 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-05-11 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure and mechanism of a methyltransferase ribozyme.
Nat.Chem.Biol., 18, 2022
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3D6T
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1J8G
 | | X-ray Analysis of a RNA Tetraplex r(uggggu)4 at Ultra-High Resolution | | 分子名称: | 5'-R(*UP*GP*GP*GP*GP*U)-3', CALCIUM ION, SODIUM ION, ... | | 著者 | Deng, J, Xiong, Y, Sundaralingam, M. | | 登録日 | 2001-05-21 | | 公開日 | 2001-11-23 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (0.61 Å) | | 主引用文献 | X-ray analysis of an RNA tetraplex (UGGGGU)(4) with divalent Sr(2+) ions at subatomic resolution (0.61 A).
Proc.Natl.Acad.Sci.USA, 98, 2001
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1IK5
 | | Crystal Structure of a 14mer RNA Containing Double UU Bulges in Two Crystal Forms: A Novel U*(AU) Intramolecular Base Triple | | 分子名称: | 5'-R(*GP*GP*UP*AP*UP*UP*UP*CP*GP*GP*UP*AP*(CBR)P*C)-3', 5'-R(*GP*GP*UP*AP*UP*UP*UP*UP*GP*GP*UP*AP*(CBR)P*C)-3', MAGNESIUM ION | | 著者 | Deng, J, Xiong, Y, Sudarsanakumar, C, Shi, K, Sundaralingam, M. | | 登録日 | 2001-05-02 | | 公開日 | 2001-11-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of two forms of a 14-mer RNA/DNA chimer duplex with double UU bulges: a novel intramolecular U*(A x U) base triple.
RNA, 7, 2001
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1JUX
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1LNT
 | | Crystal Structure of the Highly Conserved RNA Internal Loop of SRP | | 分子名称: | 5'-R(*CP*GP*GP*AP*AP*GP*CP*AP*GP*(CBV)P*GP*C)-3', 5'-R(*GP*CP*GP*UP*CP*AP*GP*GP*UP*CP*(CBV)P*G)-3', CALCIUM ION, ... | | 著者 | Deng, J, Xiong, Y, Pan, B, Sundaralingam, M. | | 登録日 | 2002-05-03 | | 公開日 | 2003-06-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of an RNA dodecamer containing a fragment from SRP domain IV of Escherichia coli.
Acta Crystallogr.,Sect.D, 59, 2003
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472D
 | | STRUCTURE OF AN OCTAMER RNA WITH TANDEM GG/UU MISPAIRS | | 分子名称: | RNA (5'-R(*GP*UP*AP*GP*GP*CP*AP*C)-3'), RNA (5'-R(*GP*UP*GP*UP*UP*UP*AP*C)-3') | | 著者 | Deng, J, Sundaralingam, M. | | 登録日 | 1999-05-14 | | 公開日 | 2000-11-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Synthesis and crystal structure of an octamer RNA r(guguuuac)/r(guaggcac) with G.G/U.U tandem wobble base pairs: comparison with other tandem G.U pairs.
Nucleic Acids Res., 28, 2000
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6WIG
 | | Structure of STENOFOLIA Protein HD domain bound with DNA | | 分子名称: | DNA (5'-D(P*CP*TP*TP*GP*AP*AP*TP*AP*AP*AP*TP*CP*AP*TP*TP*AP*AP*TP*TP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*AP*AP*TP*TP*AP*AP*TP*GP*AP*TP*TP*TP*AP*TP*TP*CP*AP*AP*G)-3'), STENOFOLIA | | 著者 | Deng, J, Peng, S, Pathak, P. | | 登録日 | 2020-04-09 | | 公開日 | 2021-08-11 | | 最終更新日 | 2022-02-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the unique tetrameric STENOFOLIA homeodomain bound with target promoter DNA.
Acta Crystallogr D Struct Biol, 77, 2021
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7U8X
 | | hTRAP1 with inhibitors | | 分子名称: | Heat shock protein 75 kDa, mitochondrial, [5-(4-fluoro-2H-isoindole-2-carbonyl)-2-hydroxyphenyl](5-methoxy-2H-isoindol-2-yl)methanone | | 著者 | Deng, J, Matts, R, Peng, S. | | 登録日 | 2022-03-09 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Elucidation of novel TRAP1-Selective inhibitors that regulate mitochondrial processes.
Eur.J.Med.Chem., 258, 2023
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7U8W
 | | hTRAP1 with inhibitors | | 分子名称: | Heat shock protein 75 kDa, mitochondrial, [5-(4-fluoro-2H-isoindole-2-carbonyl)-2-hydroxyphenyl](5-fluoro-2H-isoindol-2-yl)methanone | | 著者 | Deng, J, Matts, R, Peng, S. | | 登録日 | 2022-03-09 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.706 Å) | | 主引用文献 | Elucidation of novel TRAP1-Selective inhibitors that regulate mitochondrial processes.
Eur.J.Med.Chem., 258, 2023
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7U8U
 | | hTRAP1 with inhibitors | | 分子名称: | Heat shock protein 75 kDa, mitochondrial, [2-hydroxy-5-(2H-isoindole-2-carbonyl)phenyl]{5-[3-(triphenyl-lambda~5~-phosphanyl)propoxy]-2H-isoindol-2-yl}methanone | | 著者 | Deng, J, Matts, R, Peng, S. | | 登録日 | 2022-03-09 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.065 Å) | | 主引用文献 | Elucidation of novel TRAP1-Selective inhibitors that regulate mitochondrial processes.
Eur.J.Med.Chem., 258, 2023
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7U8V
 | | hTRAP1 with inhibitors | | 分子名称: | (4-hydroxy-1,3-phenylene)bis[(2H-isoindol-2-yl)methanone], Heat shock protein 75 kDa, mitochondrial | | 著者 | Deng, J, Matts, R, Peng, S. | | 登録日 | 2022-03-09 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.448 Å) | | 主引用文献 | Elucidation of novel TRAP1-Selective inhibitors that regulate mitochondrial processes.
Eur.J.Med.Chem., 258, 2023
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7UR3
 | | Hsp90 alpha inhibitor | | 分子名称: | (5-fluoro-1,3-dihydro-2H-isoindol-2-yl){4-hydroxy-3-[(2S)-2-hydroxy-5-phenylpentan-2-yl]phenyl}methanone, Heat shock protein HSP 90-alpha | | 著者 | Deng, J, Peng, S, Balch, M, Matts, R. | | 登録日 | 2022-04-21 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-Activity Relationship Study of Tertiary Alcohol Hsp90 alpha-Selective Inhibitors with Novel Binding Mode.
Acs Med.Chem.Lett., 13, 2022
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5UC4
 | | Hsp90b N-terminal domain with inhibitors | | 分子名称: | 5-Hydroxy-4-(isoindoline-2-carbonyl)-2-isopropylbenzaldehyde, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Deng, J, Peng, S, Balch, M, Matts, R. | | 登録日 | 2016-12-21 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor.
Nat Commun, 9, 2018
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6BR8
 | | Structure of A6 reveals a novel lipid transporter | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, Protein A6 homolog, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | 著者 | Deng, J, Peng, S, Pathak, P. | | 登録日 | 2017-11-30 | | 公開日 | 2018-06-20 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BR9
 | | Structure of A6 reveals a novel lipid transporter | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, Protein A6 homolog, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | 著者 | Deng, J, Peng, S, Pathak, P. | | 登録日 | 2017-11-30 | | 公開日 | 2018-06-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4W60
 | | The structure of Vaccina virus H7 protein displays A Novel Phosphoinositide binding fold required for membrane biogenesis | | 分子名称: | Late protein H7 | | 著者 | Kolli, S, Meng, X, Wu, X, Shengjuler, D, Cameron, C.E, Xiang, Y, Deng, J. | | 登録日 | 2014-08-19 | | 公開日 | 2014-12-31 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure-function analysis of vaccinia virus h7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication.
J.Virol., 89, 2015
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4W5X
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7RY0
 | | human Hsp90_MC domain structure | | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, Heat shock protein HSP 90-alpha | | 著者 | Peng, S, Deng, J, Matts, R. | | 登録日 | 2021-08-24 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of the key residue W320 responsible for Hsp90 conformational change.
J.Biomol.Struct.Dyn., 2022
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